Results 41 to 50 of about 1,201,455 (266)

Efficacy of intraarticular dexamethasone for postoperative analgesia after arthroscopic knee surgery

Journal of Anaesthesiology Clinical Pharmacology, 2014
Background and Aims: In an attempt to improve the recovery and early rehabilitation after arthroscopic knee surgery, various medications have been administered via intra-articular route to prolong the duration and improve the quality of postoperative ...
D. P. Bhattacharjee, Chaitali Biswas, Purba Haldar, Sujata Ghosh, Gautam Piplai, J. Rudra   +5 more
semanticscholar   +1 more source

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

Annals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije, Sara T. De Palma, Josine E. G. Vaes, Katiuscia Dallaglio, Giorgia Volpi, Diego Ardigò, Sabine van Rijt, Frank van Bel, Manon J. N. L. Benders, Cora H. A. Nijboer   +9 more
wiley   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård, Caroline Theilgaard Thorarinsson, Jan Nielsen, Mette Louise Andersen, Jens Kjeldsen, Torben Knudsen, Rahul S. Dalal   +6 more
wiley   +1 more source

Variations in Human Trigeminal and Facial Nerve Branches and Foramina Identified by Dissection and Microcomputed Tomography

Clinical Anatomy, EarlyView.
ABSTRACT The aim of this study was to identify branches of the trigeminal and facial nerves (FNs) relevant to surgical incisions and injections and the scalp block techniques in the frontotemporal region, and to determine their relationships with superficial vascular structures and bony landmarks.
Hannah L. Grimes, Valentina Pizzuti, Maria A. Wright, Kane P. J. Colston, Thomas Santarius, Susan Jones   +5 more
wiley   +1 more source

A rare mental foramen variation and the role of cone‐beam computed tomography in preventing nerve injury: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background The interforaminal space is frequently used for dental implant placement due to its strategic location between the bilateral mental foramina. However, neurosensory disturbances following surgical intervention near the mental foramen (MF) can occur in up to 43% of cases.
Magdalena Orlowska, Hend Abulatifa, Muhammad H. A. Saleh, Hom‐Lay Wang   +3 more
wiley   +1 more source

Randomised double‐blind comparison of ondansetron and droperidol to prevent postoperative nausea and vomiting associated with patient‐controlled analgesia [PDF]

, 2001
Julian Millo, M. Siddons, R. J. Innes, P. S. Laurie   +3 more
openalex   +1 more source

Dexmedetomidine and Fentanyl for Postoperative Analgesia in Patients Undergoing Abdominal Surgery: Randomised Controlled Trial

, 2021
PRASHANT SACHAN, Prem Raj Singh, Sateesh Verma, Brij Bihari Kushwaha   +3 more
openalex   +1 more source

Design, Synthesis, and Biological Characterization of Macromolecular Ester Prodrugs of a Selective Cyclooxygenase‐2 Inhibitor

ChemMedChem, EarlyView.
Two macromolecular ester prodrugs of a COX‐2 inhibitor are designed and synthesized. They are based on two different oligo(ethylene glycol) spacers linking the COX‐2 inhibitor to hyaluronic acid. The spacers are designed to differ in the sensitivity to the hydrolytic conditions.
Mario Saletti, Marco Paolino, Jacopo Venditti, Germano Giuliani, Antonietta Rossi, Danilo D’Avino, Sara Perna, Ina Varfaj, Roccaldo Sardella, Antonio Macchiarulo, Samuele Maramai, Stefania Lamponi, Andrea Cappelli, Maurizio Anzini   +13 more
wiley   +1 more source

The use of Ketamine as Rescue Analgesia in the Recovery Room following Morphine Administration—A Double-Blind Randomised Controlled Trial in Postoperative Patients [PDF]

, 2006
A. Gillies, David E. Lindholm, Margaret Angliss, A. Orr   +3 more
openalex   +1 more source