Results 101 to 110 of about 10,231,702 (322)

Neuronal Synchronization Can Control the Energy Efficiency of Inter-Spike Interval Coding [PDF]

, 2018
The role of synchronous firing in sensory coding and cognition remains controversial. While studies, focusing on its mechanistic consequences in attentional tasks, suggest that synchronization dynamically boosts sensory processing, others failed to find ...
Ghavami, Siavash, Lahouti, Farshad, Rahmati, Vahid, Schwabe, Lars   +3 more
core   +1 more source

Synaptic partner prediction from point annotations in insect brains

, 2018
High-throughput electron microscopy allows recording of lar- ge stacks of neural tissue with sufficient resolution to extract the wiring diagram of the underlying neural network.
A Kreshuk, A Kreshuk, A Kreshuk, B Staffler, C Becker, N Kasthuri, O Ronneberger, S Dorkenwald, V Jagadeesh   +8 more
core   +1 more source

Key Connectomes and Synaptic‐Compartment‐Specific Risk Genes Drive Pathological α‐Synuclein Spreading

Advanced Science, EarlyView.
Utilizing a stereotaxic injection mouse model and a novel mathematical approach, this study uncovers key subnetworks that drive pathological α‐synuclein (α‐Syn) progression in Parkinson's disease (PD). Remarkably, just 2% of the strongest connections in the connectome are sufficient to predict its spread.
Yuanxi Li, Justin Torok, Shujing Zhang, Jessica Ding, Ning Wang, Courtney Lau, Shruti Kulkarni, Chaitali Anand, Julie Tran, Michael Cheng, Claire Lo, Binbin Lu, Yanzi Sun, Robert Damoiseaux, Xia Yang, Ashish Raj, Chao Peng   +16 more
wiley   +1 more source

SNAP-25, a Known Presynaptic Protein with Emerging Postsynaptic Functions

Frontiers in Synaptic Neuroscience, 2016
A hallmark of synaptic specializations is their dependence on highly organized complexes of proteins that interact with each other. The loss or modification of key synaptic proteins directly affects the properties of such networks, ultimately impacting ...
F. Antonucci, I. Corradini, G. Fossati, Romana Tomasoni, E. Menna, M. Matteoli   +5 more
semanticscholar   +1 more source

Unraveling Neurodevelopment: Synergistic Effects of Intrinsic Genetic Programs and Extrinsic Environmental Cues

Advanced Science, EarlyView.
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang, Shukui Zhang, Huiyang Jia, Fen Ji, Jianwei Jiao   +4 more
wiley   +1 more source

Single dendrite-targeting interneurons generate branch-specific inhibition.

Frontiers in Neural Circuits, 2014
Microcircuits composed of dendrite-targeting inhibitory interneurons and pyramidal cells are fundamental elements of cortical networks, however, the impact of individual interneurons on pyramidal dendrites is unclear.
Caleb eStokes, Corinne eTeeter, Jeffry eIsaacson   +2 more
doaj   +1 more source

Residual Stresses and Micro‐voids Propel Metal Diffusion for Filament‐Based Memristors

Advanced Science, EarlyView.
Introducing non‐reactive nitrogen during silver sputtering enables low‐voltage (<60 mV) switching in memristors via nano‐void formation and residual stresses in the gigapascal range. This promotes sub‐micron filamentation and neuromorphic behaviors, including multi‐peak synaptic responses.
Joel Y.Y. Loh, Jason Yuan, Samuel Moor‐Smith, Adam Glustein, Gloria Vytas, Will Taylor, Andres Lombo, Richard J. Curry, Nazir Pyarali Kherani   +8 more
wiley   +1 more source

Modeling the Contributions of the Exocytotic Machinery and Receptor Desensitization to Short- and Long-Term Plasticity of Synapses Between Neocortical Pyramidal Neurons [PDF]

, 2001
Short-term synaptic depression (STD) refers to the progressive decrease in synaptic efficacy during a spike train. This decrease may be explained in terms of presynaptic and postsynaptic processes, such as a decrease in the probability of transmitter ...
Cohen, Michael, Okatan, Murat
core   +1 more source

Distributed Hypothesis Testing, Attention Shifts and Transmitter Dynatmics During the Self-Organization of Brain Recognition Codes [PDF]

, 1991
BP (89-A-1204); Defense Advanced Research Projects Agency (90-0083); National Science Foundation (IRI-90-00530); Air Force Office of Scientific Research (90-0175, 90-0128); Army Research Office (DAAL-03-88 ...
Carpenter, Gail A., Grossberg, Stephen
core   +1 more source

Heterointerface‐Modulated Synthetic Synapses Exhibiting Complex Multiscale Plasticity

Advanced Science, EarlyView.
An asymmetric dual‐gate heterointerface‐regulated artificial synapse (HRAS) is developed, employing distinct ion concentrations and dielectric coupling to form precise dual‐interface channels. Through lateral modulation, HRAS realizes, for the first time, the intricate interplay of lateral inhibition/enhancement and multi‐level short‐ and long‐term ...
Xingji Liu, Yao Ni, Zujun Wang, Sunfu Wei, Xiao′en Chen, Jingjie Lin, Lu Liu, Boyang Yu, Yue Yu, Dengyun Lei, Yayi Chen, Jianfeng Zhang, Jing Qi, Wei Zhong, Yuan Liu   +14 more
wiley   +1 more source