Results 81 to 90 of about 136,994 (263)
Advanced Science, EarlyView.A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu +15 more
wiley +1 more source
Neuromorphic sensing of TDP-43 antigen–antibody binding using an ionic liquid channel field effect transistor [PDF]
APL Electronic DevicesTransactive response DNA binding protein (TDP-43) is a biomarker for neurodegenerative diseases, including motor neuron disease. We report an electrolyte channel neuromorphic biosensor that detects the presence of TDP-43 antigen at physiologically ...
Luke A. Sylvander +8 more
doaj +1 more source
Advanced Science, EarlyView.A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang +10 more
wiley +1 more source
Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review
Advanced Science, EarlyView.Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh +8 more
wiley +1 more source
Electromagnetic Radiation Stimulated Learning in Perovskite Nickelates
Advanced Science, EarlyView.ABSTRACT Biological plasticity refers to the ability of synapses to strengthen or weaken over time. These adaptive properties play a fundamental role in learning and memory, spanning many orders of magnitude in timescales. Short‐term plasticity (STP) arises from rapid correlative activity, while long‐term plasticity (LTP) is governed by slower ...
Ranjan Kumar Patel +8 more
wiley +1 more source
Advanced Science, EarlyView.Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu +8 more
wiley +1 more source
Advanced Science, EarlyView.A nanoporous SiO2 memristor enabling reconfigurable volatile and non‐volatile switching within a single device is demonstrated. The dual‐mode functionality supports both physical reservoir dynamics and synaptic weight storage, allowing unified hardware implementation of reservoir computing for temporal information processing, including image and ...
Bohao Ding +5 more
wiley +1 more source
Mediation of slow-inhibitory postsynaptic potentials [PDF]
Nature, 1985 PATRICIA SHINNICK-GALLAGHER +1 more
openaire +3 more sources
Advanced Science, EarlyView.Here, we present an optoelectronic synaptic memtransistor (OSMT) integrating photoresponsive IGZO with contact‐engineered HfO2, enabling electrically and optically tunable synaptic weights. The device demonstrates broad range of tunable conductance states and array‐level image processing, highlighting its potential for intelligent machine vision ...
Donghyun Kang +6 more
wiley +1 more source
Advanced Science, EarlyView.A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang +17 more
wiley +1 more source