Results 61 to 70 of about 8,644,509 (305)

Neuromodulated Spike-Timing-Dependent Plasticity and Theory of Three-Factor Learning Rules

Frontiers in Neural Circuits, 2016
Classical Hebbian learning puts the emphasis on joint pre- and postsynaptic activity, but neglects the potential role of neuromodulators. Since neuromodulators convey information about novelty or reward, the influence of neuromodulatorson synaptic ...
Wulfram eGerstner, Nicolas eFremaux
doaj   +1 more source

Illustration of the postsynaptic kernels used in this analysis, and an example of a resulting postsynaptic membrane potential.

, 2016
(A) The time course of the postsynaptic current kernel α. (B) The PSP kernel ϵ. (C) The reset kernel κ. (D) The resulting membrane potential ui as defined by Eq (1). In this example, a single presynaptic spike is received at tj = 0 ms, and a postsynaptic
André Grüning (2993805), Brian Gardner (786323)   +1 more
core   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Advanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan, Hocheon Yoo, Benoît H. Lessard, Ioannis Kymissis, Chang‐Hyun Kim   +4 more
wiley   +1 more source

Parameters of networks used in simulations (exc: excitatory, inh: inhibitory, pop: population, amp: amplitude, CP: connection probability, PSP: postsynaptic potential, PSC: postsynaptic current, assem: assembly, conn: connections).

, 2018
Parameters of networks used in simulations (exc: excitatory, inh: inhibitory, pop: population, amp: amplitude, CP: connection probability, PSP: postsynaptic potential, PSC: postsynaptic current, assem: assembly, conn: connections).
Moritz Deger (306447), Wulfram Gerstner (129561), Hesam Setareh (5487965)   +2 more
core   +1 more source

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Grothe, Benedikt, Meyer, Elisabeth M. M., Felmy, Felix, Porres, Christian P.   +3 more
core   +1 more source

Electrically Induced Phase Transition and Synaptic Functionality in MoTe2/Graphene Memristors

Advanced Functional Materials, EarlyView.
An electrically induced reversible 2H ↔ 1T′ phase transition is demonstrated in a vertical Au/Ti/MoTe2/graphene memristor with a laterally contacted graphene electrode. Resistive switching proceeds through a compositionally invariant amorphous/2H ↔ amorphous/1T′ transformation, in which a self‐formed amorphous MoTe2 interfacial region is proposed to ...
Chien‐Hua Wang, Mu‐Pai Lee, Jhen‐Dong Tsai, Liang‐Ying Hsieh, Jui‐Yuan Chen, Chun‐Wei Huang, Yen‐Fu Lin, Wen‐Wei Wu   +7 more
wiley   +1 more source

Mouse-derived Synaptosomes Trypsin Cleavage Assay to Characterize Synaptic Protein Sub-localization

Bio-Protocol
Neurons communicate through neurotransmission at highly specialized junctions called synapses. Each neuron forms numerous synaptic connections, consisting of presynaptic and postsynaptic terminals.
Jasmeet Shergill, Domenico Azarnia Tehran   +1 more
doaj   +1 more source

Calcium accumulation in visual interneurons of the fly: stimulus dependence and relationship to membrane potential [PDF]

, 1995
Egelhaaf M, Borst A. Calcium accumulation in visual interneurons of the fly: stimulus dependence and relationship to membrane potential. Journal of neurophysiology. 1995;73(6):2540-2552.1.
Egelhaaf, M., Borst, Alexander, Egelhaaf, Martin ; https://orcid.org/, Borst, A., M. Egelhaaf, A. Borst   +5 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Shaping synaptic learning by the duration of postsynaptic action potential in a new STDP model. [PDF]

PLoS ONE, 2014
Single spikes and their timing matter in changing synaptic efficacy, which is known as spike-timing-dependent plasticity (STDP). Most previous studies treated spikes as all-or-none events, and considered their duration and magnitude as negligible.
Youwei Zheng, Lars Schwabe
doaj   +1 more source