Results 41 to 50 of about 195,524 (202)

Postsynaptic activity of inhibitory neurons evokes hemodynamic fMRI responses

NeuroImage, 2021
Functional MRI responses are localized to the synaptic sites of evoked inhibitory neurons, but it is unknown whether, or by what mechanisms, these neurons initiate functional hyperemia.
Alexander John Poplawsky, Bistra Iordanova, Alberto L. Vazquez, Seong-Gi Kim, Mitsuhiro Fukuda   +4 more
doaj   +1 more source

Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex [PDF]

Journal of Integrative Neuroscience, 2020
Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects.
Jia Hui Wong, Faruque Reza, Sangu Muthuraju, Huei Gau Chuang, Jingli Zhang, Mohd Harizal Senik, Siti Rafidah Yusof, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Nor Hadiani Ismail, Jafri Malin Abdullah
doaj   +1 more source

Double Inverse Stochastic Resonance with Dynamic Synapses

, 2016
We investigate the behavior of a model neuron that receives a biophysically-realistic noisy post-synaptic current based on uncorrelated spiking activity from a large number of afferents.
Barreto, E., Ozer, M., So, P., Torres, J. J., Uzuntarla, M.   +4 more
core   +1 more source

Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]

, 1977
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner, B. Katz, E. Gergens, E. H. Lambert, F. Colomo, F. H. Norris, H. Ter�v�inen, J. I. Simpson, K. Koizumi, K. Ricker, M. A. Kamenskaya, M. A. Kamenskaya, M. Otsuka, P. Grafe, R. C. Scaer, S. D. Erulkar, S. J. Oh, U. Sonnhof, U. Sonnhof, W. C. Wiederholt   +19 more
core   +1 more source

Spike-timing dependent plasticity in inhibitory circuits

Frontiers in Synaptic Neuroscience, 2010
Inhibitory circuits in the brain rely on GABA-releasing interneurons. For long, inhibitory circuits were considered weakly plastic in the face of patterns of neuronal activity that trigger long-term changes in the synapses between excitatory principal ...
Karri P Lamsa, Dimitri M. Kullmann, Melanie A Woodin   +2 more
doaj   +1 more source

A Novel Optical Quantal Analysis of Miniature Events Reveals Enhanced Frequency Following Amyloid β Exposure

Frontiers in Cellular Neuroscience, 2020
Non-evoked miniature release of neurotransmitters is increasingly recognized as playing an important role in neural function and is implicated in synaptic plasticity, metaplasticity, and homeostasis.
Henry B. C. Taylor, Rudi Tong, Rudi Tong, Alexander F. Jeans, Nigel J. Emptage   +4 more
doaj   +1 more source

Functional labeling of individualized postsynaptic neurons using optogenetics and trans-Tango in Drosophila (FLIPSOT).

PLoS Genetics
A population of neurons interconnected by synapses constitutes a neural circuit, which performs specific functions upon activation. It is essential to identify both anatomical and functional entities of neural circuits to comprehend the components and ...
Allison N Castaneda, Ainul Huda, Iona B M Whitaker, Julianne E Reilly, Grace S Shelby, Hua Bai, Lina Ni   +6 more
doaj   +1 more source

Transmitter release from cochlear hair cells is phase locked to cyclic stimuli of different intensities and frequencies [PDF]

, 2012
The auditory system processes time and intensity through separate brainstem pathways to derive spatial location as well as other salient features of sound.
Goutman, Juan Diego
core   +1 more source

Changes in synaptic transmission of substantia gelatinosa neurons after spinal cord hemisection revealed by analysis using in vivo patch-clamp recording

Molecular Pain, 2016
Background After spinal cord injury, central neuropathic pain develops in the majority of spinal cord injury patients. Spinal hemisection in rats, which has been developed as an animal model of spinal cord injury in humans, results in hyperexcitation of ...
Yuji Kozuka MD, Mikito Kawamata MD, Hidemasa Furue PhD, Takashi Ishida MD, Satoshi Tanaka MD, Akiyoshi Namiki MD, Michiaki Yamakage MD   +6 more
doaj   +1 more source

Neuromodulated Spike-Timing-Dependent Plasticity and Theory of Three-Factor Learning Rules

Frontiers in Neural Circuits, 2016
Classical Hebbian learning puts the emphasis on joint pre- and postsynaptic activity, but neglects the potential role of neuromodulators. Since neuromodulators convey information about novelty or reward, the influence of neuromodulatorson synaptic ...
Wulfram eGerstner, Nicolas eFremaux
doaj   +1 more source