Results 21 to 30 of about 8,644,509 (305)

Retrograde Synaptic Signaling Mediated by K+ Efflux through Postsynaptic NMDA Receptors

open access: yesCell Reports, 2013
Synaptic NMDA receptors (NMDARs) carry inward Ca2+ current responsible for postsynaptic signaling and plasticity in dendritic spines. Whether the concurrent K+ efflux through the same receptors into the synaptic cleft has a physiological role is not ...
Pei-Yu Shih   +7 more
doaj   +1 more source

Impairment Mechanisms and Intervention Approaches for Aged Human Neuromuscular Junctions

open access: yesFrontiers in Molecular Neuroscience, 2020
The neuromuscular junction (NMJ) is a chemical synapse formed between a presynaptic motor neuron and a postsynaptic muscle cell. NMJs in most vertebrate species share many essential features; however, some differences distinguish human NMJs from others ...
Yomna Badawi   +2 more
doaj   +1 more source

Molecular model of postsynaptic potential. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1975
A molecular model of the excitatory postsynaptic membrane is given in terms of two biochemical cycles intimately associated: an acetylcholine cycle and a calcium cycle. The acetylcholine controls the Na ionophores while calcium ions control the tk ionophore.
D M, Dubois, E, Schoffeniels
openaire   +2 more sources

Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction [PDF]

open access: yes, 2004
The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits, Drosophila glutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at the Drosophila neuromuscular ...
Portman, Scott L.   +5 more
core   +1 more source

Occurrence of Ordered and Disordered Structural Elements in Postsynaptic Proteins Supports Optimization for Interaction Diversity

open access: yesEntropy, 2019
The human postsynaptic density is an elaborate network comprising thousands of proteins, playing a vital role in the molecular events of learning and the formation of memory.
Annamária Kiss-Tóth   +6 more
doaj   +1 more source

Synaptic transfer of dynamic motion information between identified neurons in the visual system of the blowfly [PDF]

open access: yes, 2003
Warzecha A-K, Kurtz R, Egelhaaf M. Synaptic transfer of dynamic motion information between identified neurons in the visual system of the blowfly. Neuroscience.
Egelhaaf, Martin ; https://orcid.org/   +2 more
core   +1 more source

Antagonistic interactions between two Neuroligins coordinate pre- and postsynaptic assembly

open access: yes, 2021
As a result of developmental synapse formation, the presynaptic neurotransmitter release machinery becomes accurately matched with postsynaptic neurotransmitter receptors.
Escher, Marc J. F.   +9 more
core   +1 more source

GABAergic synaptic transmission regulates calcium influx during spike-timing dependent plasticity

open access: yesFrontiers in Synaptic Neuroscience, 2010
Coincident pre- and postsynaptic activity of hippocampal neurons alters the strength of gamma-aminobutyric acid (GABAA)-mediated inhibition through a Ca2+-dependent regulation of cation-chloride cotransporters.
Trevor Balena   +2 more
doaj   +1 more source

Long-term potentiation through calcium-mediated N-Cadherin interaction is tightly controlled by the three-dimensional architecture of the synapse [PDF]

open access: yes, 2013
Poster presentation: Twenty Second Annual Computational Neuroscience Meeting: CNS*2013. Paris, France. 13-18 July 2013. The synaptic cleft is an extracellular domain that is capable of relaying a presynaptically received electrical signal by diffusive ...
Queisser, Sean Gillian   +3 more
core   +1 more source

Human synapses show a wide temporal window for spike-timing-dependent plasticity

open access: yesFrontiers in Synaptic Neuroscience, 2010
Throughout our lifetime, activity-dependent changes in neuronal connection strength enable the brain to refine neural circuits and learn based on experience.
Guilherme T Silva   +7 more
doaj   +1 more source

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