Results 11 to 20 of about 8,644,509 (305)

Effects of Ketamine on Neuronal Spontaneous Excitatory Postsynaptic Currents and Miniature Excitatory Postsynaptic Currents in the Somatosensory Cortex of Rats

open access: yesIranian Journal of Medical Sciences, 2016
Background: Ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. The mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown.
Chengdong Yuan   +6 more
doaj   +1 more source

EPSPs in rat neocortical neurons in vitro. I. Electrophysiological evidence for two distinct EPSPs [PDF]

open access: yes, 1989
1. To investigate excitatory postsynaptic potentials (EPSPs), intracellular recordings were performed in layer II/III neurons of the rat medial frontal cortex.
Sutor, Bernd, Hablitz, John H.
core   +2 more sources

EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]

open access: yes, 1989
1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
J. J. Hablitz   +3 more
core   +2 more sources

Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]

open access: yes, 1975
The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J.   +9 more
core   +1 more source

Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neurons in vitro [PDF]

open access: yes, 1987
1. The characteristics of long-duration inhibitory postsynaptic potentials (l-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from anin vitro slice preparation.
Howe, James R.   +2 more
core   +1 more source

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

open access: yes, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Buwalda, Bauke   +23 more
core   +1 more source

Modeling Calcium Dynamics and Inhibition Based Synaptic Plasticity in Dendritic Spines

open access: yesMathematical Modelling and Analysis, 2014
Inhibitory synapses through GABAergic channels not only change spine's calcium dynamics but also modulate postsynaptic current mediated through glutamate receptors.
Muhammad Dur-e-Ahmad
doaj   +1 more source

Influence of Mpv17 on Hair-Cell Mitochondrial Homeostasis, Synapse Integrity, and Vulnerability to Damage in the Zebrafish Lateral Line

open access: yesFrontiers in Cellular Neuroscience, 2021
Noise exposure is particularly stressful to hair-cell mitochondria, which must produce enough energy to meet high metabolic demands as well as regulate local intracellular Ca2+ concentrations.
Melanie Holmgren   +2 more
doaj   +1 more source

Brain Dystrophin in Duchenne Dystrophy

open access: yesPediatric Neurology Briefs, 1995
To define the potential pathogenic role of dystrophin deficiency in the cognitive impairment characteristic of Duchenne muscular dystrophy (DMD), the protein in brain cortical synapses of an 8-year-old patient examined at autopsy and an age-matched ...
J Gordon Millichap
doaj   +1 more source

Dendritic spines as chemical and electrical compartments : a two-photon imaging study in the hippocampus of the rat [PDF]

open access: yes, 2008
Most excitatory synapses are located on small dendritic protrusions called spines. So far, the function of dendritic spines is not fully understood. Imaging experiments have shown that spines can compartmentalize second messengers such as Ca2+.
Müller-Grunditz, Åsa
core   +1 more source

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