Results 31 to 40 of about 136,994 (263)

A Novel Optical Quantal Analysis of Miniature Events Reveals Enhanced Frequency Following Amyloid β Exposure

Frontiers in Cellular Neuroscience, 2020
Non-evoked miniature release of neurotransmitters is increasingly recognized as playing an important role in neural function and is implicated in synaptic plasticity, metaplasticity, and homeostasis.
Henry B. C. Taylor, Rudi Tong, Rudi Tong, Alexander F. Jeans, Nigel J. Emptage   +4 more
doaj   +1 more source

Increased ribosomal protein levels and protein synthesis in the striatal synaptosome of Shank3-overexpressing transgenic mice

Molecular Brain, 2021
The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders.
Chunmei Jin, Yeunkum Lee, Hyojin Kang, Kwon Jeong, Joori Park, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Hyunyoung Seong, Yoonhee Kim, Hosung Jung, Jin Young Kim, Yoon Ki Kim, Kihoon Han   +13 more
doaj   +1 more source

Postsynaptic activity of inhibitory neurons evokes hemodynamic fMRI responses

NeuroImage, 2021
Functional MRI responses are localized to the synaptic sites of evoked inhibitory neurons, but it is unknown whether, or by what mechanisms, these neurons initiate functional hyperemia.
Alexander John Poplawsky, Bistra Iordanova, Alberto L. Vazquez, Seong-Gi Kim, Mitsuhiro Fukuda   +4 more
doaj   +1 more source

Acute application of Centella asiatica extract enhanced AMPAR-mediated postsynaptic currents in rat entorhinal cortex [PDF]

Journal of Integrative Neuroscience, 2020
Centella asiatica is notable for its wide range of biological activities beneficial to human health, particularly its cognitive enhancement and neuroprotective effects.
Jia Hui Wong, Faruque Reza, Sangu Muthuraju, Huei Gau Chuang, Jingli Zhang, Mohd Harizal Senik, Siti Rafidah Yusof, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Nor Hadiani Ismail, Jafri Malin Abdullah
doaj   +1 more source

Spectrally Selective Bipolar Self‐Powered Opto‐Synaptic Responses in Tandem 2D van Der Waals Ferroelectric Heterojunctions

Advanced Functional Materials, EarlyView.
Tandem 2D vdW ferroelectric heterojunctions enable spectrally selective, self‐powered bipolar opto‐synaptic responses for retinal ON/OFF bipolar cell emulation and wavelength‐programmable logic operations. This work establishes vdW ferroelectric heterojunctions as a compelling materials platform for energy‐efficient, adaptive, and human‐like artificial
Rajiv Kumar Pandey, Chang Yong Park, Cheolhwa Jang, Taeho Kang, Sungjoo Lee   +4 more
wiley   +1 more source

Functional labeling of individualized postsynaptic neurons using optogenetics and trans-Tango in Drosophila (FLIPSOT).

PLoS Genetics
A population of neurons interconnected by synapses constitutes a neural circuit, which performs specific functions upon activation. It is essential to identify both anatomical and functional entities of neural circuits to comprehend the components and ...
Allison N Castaneda, Ainul Huda, Iona B M Whitaker, Julianne E Reilly, Grace S Shelby, Hua Bai, Lina Ni   +6 more
doaj   +1 more source

Changes in synaptic transmission of substantia gelatinosa neurons after spinal cord hemisection revealed by analysis using in vivo patch-clamp recording

Molecular Pain, 2016
Background After spinal cord injury, central neuropathic pain develops in the majority of spinal cord injury patients. Spinal hemisection in rats, which has been developed as an animal model of spinal cord injury in humans, results in hyperexcitation of ...
Yuji Kozuka MD, Mikito Kawamata MD, Hidemasa Furue PhD, Takashi Ishida MD, Satoshi Tanaka MD, Akiyoshi Namiki MD, Michiaki Yamakage MD   +6 more
doaj   +1 more source

Spike-timing dependent plasticity in inhibitory circuits

Frontiers in Synaptic Neuroscience, 2010
Inhibitory circuits in the brain rely on GABA-releasing interneurons. For long, inhibitory circuits were considered weakly plastic in the face of patterns of neuronal activity that trigger long-term changes in the synapses between excitatory principal ...
Karri P Lamsa, Dimitri M. Kullmann, Melanie A Woodin   +2 more
doaj   +1 more source

Mimicking Silent Synapse Recruitment: A SiOx/Cu‐Pancake Memristive Device For Analog Neuromorphic Computing

Advanced Functional Materials, EarlyView.
Electroforming‐free TiN/SiOx/Cu/SiOx/TiN memristive devices exploit pancake‐like Cu nanoparticles embedded in a SiOx double layer to create a heterogeneous Schottky‐barrier landscape. Under bias, oxygen‐vacancy redistribution progressively lowers local barriers and recruits initially inactive Cu‐PC pathways into a parallel conduction ensemble, enabling
Rouven Lamprecht, Ole Gronenberg, Sahitya Yarragolla, Tobias Gergs, Richard Marquardt, Victor Witte, Jürgen Carstensen, George Popkirov, Jan Trieschmann, Lorenz Kienle, Hermann Kohlstedt   +10 more
wiley   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

Advanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long, Huanyu Zhou, Jaewan Ko, Hongwei Tan, Jaemin Lim, Yanfei Zhao, Daehan Kang, Eojin Yoon, Gyeong‐Tak Go, Somin Kim, Seung‐Woo Lee, Chan‐Yul Park, Hyojun Choi, Hyeran Kim, Hyung Joong Yun, Sung Hyuk Park, Kwan Sik Park, Jeong Woo Park, Mungeun Kim, Yong Soo Cho, Ho Won Jang, Wenqiang Yang, Min Hyuk Park, Wan Ki Bae, Sebastiaan van Dijken, Joona Bang, Tae‐Woo Lee   +26 more
wiley   +1 more source