Results 241 to 250 of about 10,942,539 (365)

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Age-dependent increases in dorsal hippocampal postsynaptic α5GABA-a receptors may be lost in a rat model of Alzheimer's disease. [PDF]

Sci Rep
George JC, Tipton AE, Bonfa NVS, Farb DH, Russek SJ.   +4 more
europepmc   +1 more source

Brain‐specific potential guanine nucleotide exchange factor for Arf, synArfGEF (Po), is localized to postsynaptic density

Journal of Neurochemistry, 2004
Y. Inaba, Q. Tian, A. Okano, Jingping Zhang, H. Sakagami, S. Miyazawa, Weidong Li, A. Komiyama, K. Inokuchi, H. Kondo, Tatsuo Suzuki   +10 more
semanticscholar   +1 more source

Comparison of the effectiveness, safety and tolerability of Perampanel and Levetiracetam as monotherapy in Chinese patients with focal‐onset seizures: A single‐center, ambispective, open‐label, real‐world observational study

Epilepsia Open, EarlyView.
Abstract Objective To compare the effectiveness and safety of Perampanel (PER) and Levetiracetam (LEV) as monotherapy in Chinese patients with focal‐onset seizures (FOS). Methods This is a single‐center, ambispective, open‐label, real‐world observational study.
Haiyan Ma, Rui Zhang, Yan Zhang, Honghao Xu, Xuefeng Qu, Yiqing Yang, Jiajia Li, Lu Yang, Qigang Zhou, Haitao Zhu   +9 more
wiley   +1 more source

Transcriptomic disruption and hypoactivity in DYT-SGCE medial ganglionic eminence-patterned inhibitory neurons. [PDF]

Brain
Li Z, Abram L, Cruz-Santos M, Petter O, Peall KJ.   +4 more
europepmc   +1 more source

The role of auditory sensory input during functional pre- and postsynaptic maturation of the calyx of Held synapse. [PDF]

, 2007
Erazo Fischer, E.
core   +1 more source

Composition of the Excitatory Postsynaptic Potentials Recorded from Rat Visual Cortical Neurons in Layer II/III: An In Vitro Electrophysiological and Pharmacological Studies.

, 1991
Yasuo Takahashi, Tetsuro Ogawa
openalex   +2 more sources

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

Epilepsia Open, EarlyView.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra   +24 more
wiley   +1 more source

Intrinsically flexible multimode reconfigurable transistors for polymorphic circuits and neuromorphic devices. [PDF]

Nat Commun
Wang W, Qiu R, Zhu J, Zhu T, Wang J, Liu D, Liang J, Wang C, Zhang S, Wang Z, Huang Q, Wang X, Zhang M.   +12 more
europepmc   +1 more source

Clock gene dysregulation in epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective Epileptic seizures show a rhythmic pattern, being more frequent at particular times of the day (e.g., only occurring during sleep), suggesting a role of the circadian rhythm. Clock genes regulate the circadian rhythm and might be involved in the pathophysiology of epilepsy.
Guilherme Fernandes‐Campos, Arjune Sen, Francesca Panin, Krithika Sundararaman   +3 more
wiley   +1 more source