Results 241 to 250 of about 10,517,225 (330)
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Downregulation of TREM2 induces autism‐like behaviors in healthy rats by impairing microglial function and triggering aberrant synaptic pruning. RA/RARα signaling pathway modulates alterations in TREM2 expression. Serum sTREM2 levels correspond to alterations in brain TREM2 expression.
Min Lu +9 more
wiley +1 more source
Whole-body connectome of a segmented annelid larva. [PDF]
Verasztó C +6 more
europepmc +1 more source
Proteomic Insight Into Alzheimer's Disease Pathogenesis Pathways
ABSTRACT Alzheimer's disease (AD) is a leading cause of dementia, but the pathogenesis mechanism is still elusive. Advances in proteomics have uncovered key molecular mechanisms underlying AD, revealing a complex network of dysregulated pathways, including amyloid metabolism, tau pathology, apolipoprotein E (APOE), protein degradation ...
Taekyung Ryu +3 more
wiley +1 more source
For the advancement of neuromorphic computing and bio‐integrated electronics, a dual‐stacked ITO/IGZO/ZrO2/Ti resistive random access memory (RRAM) device with oxygen vacancy engineering is demonstrated for reliable synaptic and nociceptive behavior. Gradual potentiation and depression, along with biologically inspired spike‐timing‐dependent plasticity
Seo‐Young Jo +4 more
wiley +1 more source
Calcium signaling in postsynaptic mitochondria: mechanisms, dynamics, and role in ATP production. [PDF]
Feofilaktova T +3 more
europepmc +1 more source

