Results 11 to 20 of about 120,482 (333)
Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure [PDF]
, 2017 The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infection.
Peeters, Charlotte +5 more
core +13 more sources
Posttranslational modifications of the cytoskeleton [PDF]
Cytoskeleton, 2021 AbstractThe cytoskeleton plays important roles in many essential processes at the cellular and organismal levels, including cell migration and motility, cell division, and the establishment and maintenance of cell and tissue architecture. In order to facilitate these varied functions, the main cytoskeletal components—microtubules, actin filaments, and ...
Brittany MacTaggart, Anna Kashina
openaire +2 more sources
Cell Discovery, 2021 Histone lysine crotonylation is a posttranslational modification with demonstrated functions in transcriptional regulation. Here we report the discovery of a new type of histone posttranslational modification, lysine methacrylation (Kmea), corresponding ...
Kyle Delaney +15 more
doaj +1 more source
Biomolecules, 2023 p300 acts as a transcription coactivator and an acetyltransferase that plays an important role in tumourigenesis and progression. In previous studies, it has been confirmed that p300 is an important regulator in regulating the evolution of malignant ...
Qingmei Zeng +5 more
doaj +1 more source
The Degradation Pathway of the Mitophagy Receptor Atg32 Is Re-Routed by a Posttranslational Modification. [PDF]
PLoS ONE, 2016 The outer mitochondrial membrane protein Atg32 is the central receptor for mitophagy, the mitochondria-specific form of autophagy. Atg32 is an unstable protein, and is rapidly degraded under conditions in which mitophagy is not induced. Here we show that
Mariia Levchenko +2 more
doaj +1 more source
Role of Glycoproteins during Fruit Ripening and Seed Development
Cells, 2021 Approximately thirty percent of the proteins synthesized in animal or plant cells travel through the secretory pathway. Seventy to eighty percent of those proteins are glycosylated. Thus, glycosylation is an important protein modification that is related
Angela Mendez-Yañez +2 more
doaj +1 more source
Glycosylation—The Most Diverse Post-Translational Modification
Biomolecules, 2022 This article is part of the Special Issue Glycosylation—The Most Diverse Post-Translational Modification [...]
Erika Staudacher +2 more
doaj +1 more source
Asian Journal of Urology, 2020 Prostate cancer (PCa) is the most commonly diagnosed cancer among men in western countries. Androgen receptor (AR) signaling plays key roles in the development of PCa. Androgen deprivation therapy (ADT) remains the standard therapy for advanced PCa.
Simeng Wen, Yuanjie Niu, Haojie Huang
doaj +1 more source
Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A [PDF]
, 2017 Ribosomal translation factors are fundamental for protein synthesis and highly conserved in all kingdoms of life. The essential eukaryotic elongation factor 1A (eEF1A) delivers aminoacyl tRNAs to the A-site of the translating 80S ribosome.
Aktories, Klaus +10 more
core +1 more source
Site-selective protein modification via disulfide rebridging for fast tetrazine/trans-cyclooctene bioconjugation [PDF]
, 2020 An inverse electron demand Diels–Alder reaction between tetrazine and trans-cyclooctene (TCO) holds great promise for protein modification and manipulation.
Chudasama, V. +6 more
core +1 more source