Results 21 to 30 of about 941,378 (248)

New Posttranslational Modification Lactylation Brings New Inspiration for the Treatment of Rheumatoid Arthritis. [PDF]

J Inflamm Res
Yue Yang,1,* Jinjie Shi,2,* Jiming Yu,3,* Xin Zhao,1 Ke Zhu,1 Shen Wang,4 Xinwen Zhang,1 Xieyu Zhang,1 Guangcheng Wei,1 Wei Cao1 1Rheumatology Department, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, People’s ...
Yang Y, Shi J, Yu J, Zhao X, Zhu K, Wang S, Zhang X, Zhang X, Wei G, Cao W.   +9 more
europepmc   +2 more sources

Proteome-Wide Analysis of Lysine 2-Hydroxyisobutyrylation in Candida albicans

mSystems, 2021
Candida albicans is the most common human fungal pathogen, causing diseases ranging from mucosal to systemic infections for both immunocompetent and immunocompromised individuals.
Hailin Zheng, Nana Song, Xiaowei Zhou, Huan Mei, Dongmei Li, Xiaofang Li, Weida Liu   +6 more
doaj   +1 more source

AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins

iScience, 2021
Summary: Protein AMPylation is a posttranslational modification with an emerging role in neurodevelopment. In metazoans two highly conserved protein AMP-transferases together with a diverse group of AMPylated proteins have been identified using chemical ...
Tobias Becker, Cedric Cappel, Francesco Di Matteo, Giovanna Sonsalla, Ewelina Kaminska, Fabio Spada, Silvia Cappello, Markus Damme, Pavel Kielkowski   +8 more
doaj   +1 more source

Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2

Cell Discovery, 2021
Histone lysine crotonylation is a posttranslational modification with demonstrated functions in transcriptional regulation. Here we report the discovery of a new type of histone posttranslational modification, lysine methacrylation (Kmea), corresponding ...
Kyle Delaney, Minjia Tan, Zhesi Zhu, Jinjun Gao, Lunzhi Dai, Sunjoo Kim, Jun Ding, Maomao He, Levon Halabelian, Lu Yang, Prabakaran Nagarajan, Mark Robert Parthun, Sangkyu Lee, Saadi Khochbin, Yujun George Zheng, Yingming Zhao   +15 more
doaj   +1 more source

Role of Glycoproteins during Fruit Ripening and Seed Development

Cells, 2021
Approximately thirty percent of the proteins synthesized in animal or plant cells travel through the secretory pathway. Seventy to eighty percent of those proteins are glycosylated. Thus, glycosylation is an important protein modification that is related
Angela Mendez-Yañez, Patricio Ramos, Luis Morales-Quintana   +2 more
doaj   +1 more source

Deep Learning–Based Advances In Protein Posttranslational Modification Site and Protein Cleavage Prediction

, 2022
Posttranslational modification (PTM) is a ubiquitous phenomenon in both eukaryotes and prokaryotes which gives rise to enormous proteomic diversity. PTM mostly comes in two flavors: covalent modification to polypeptide chain and proteolytic cleavage ...
Pakhrin, Subash C., Saigo, Hiroto, KC, Dukka, Pokharel, Suresh, KC, Dukka B., Subash C. Pakhrin, Suresh Pokharel, Hiroto Saigo, Dukka B. KC   +8 more
core   +1 more source

Posttranslational modification of CTNNBL1 protein

, 2022
Posttranslational modification of and ubiquitinated peptides in CTNNBL1 during HIV-1 infection. Posttranslational modification analysis of CTNNBL1 protein by phosphorylation, acetylation, ubiquitination, succinylation, crotonylation, and methylationTHIS ...
Liang, G (via Mendeley Data), Liang, Guoxin   +1 more
core   +1 more source

Posttranslational Modification of Waxy to Genetically Improve Starch Quality in Rice Grain. [PDF]

Int J Mol Sci, 2021
The waxy (Wx) gene, encoding the granule-bound starch synthase (GBSS), is responsible for amylose biosynthesis and plays a crucial role in defining eating and cooking quality. The waxy locus controls both the non-waxy and waxy rice phenotypes.
Adegoke TV, Wang Y, Chen L, Wang H, Liu W, Liu X, Cheng YC, Tong X, Ying J, Zhang J.   +9 more
europepmc   +2 more sources

Posttranslational regulation of androgen dependent and independent androgen receptor activities in prostate cancer

Asian Journal of Urology, 2020
Prostate cancer (PCa) is the most commonly diagnosed cancer among men in western countries. Androgen receptor (AR) signaling plays key roles in the development of PCa. Androgen deprivation therapy (ADT) remains the standard therapy for advanced PCa.
Simeng Wen, Yuanjie Niu, Haojie Huang
doaj   +1 more source

Glycosylation—The Most Diverse Post-Translational Modification

Biomolecules, 2022
This article is part of the Special Issue Glycosylation—The Most Diverse Post-Translational Modification [...]
Erika Staudacher, Els J. M. Van Damme, Guy Smagghe   +2 more
doaj   +1 more source