Results 31 to 40 of about 941,378 (248)

Role of Sp1 posttranslational modification in atherosclerosis [PDF]

Jichu yixue yu linchuang
Specific proteins (Sp) are a well-known family of transcription factors. Sp1 as a key transcription factor, specific protein 1 (Sp1) regulates the pathological process of atherosclerosis (AS) through post-translational modification (PTMs ...
ZHOU Qi, SUN Xutao, WU Siyu, QU Ying, SONG Yunjia
doaj   +1 more source

A tri-functional amino acid enables mapping of binding sites for posttranslational modification-mediated protein-protein interactions

, 2021
This is the raw data of imaging used in the paper "A tri-functional amino acid enables mapping of binding sites for posttranslational modification-mediated protein-protein interactions"
LIN, Jianwei
core   +1 more source

Nitric oxide-induced calcium release: activation of type 1 ryanodine receptor, a calcium release channel, through non-enzymatic posttranslational modification by nitric oxide

Frontiers in Endocrinology, 2013
Nitric oxide (NO) is a typical gaseous messenger involved in a wide range of biological processes. In our classical knowledge, effects of NO are largely achieved by activation of soluble guanylyl cyclase to form cyclic guanosine-3’, 5’-monophosphate ...
Sho eKakizawa
doaj   +1 more source

Targeted Quantification of Phosphorylation Sites Identifies STRIPAK-Dependent Phosphorylation of the Hippo Pathway-Related Kinase SmKIN3

mBio, 2021
Phosphorylation and dephosphorylation of proteins are fundamental posttranslational modifications that determine the fine-tuning of their biological activity.
Valentina Stein, Bernhard Blank-Landeshammer, Ramona Märker, Albert Sickmann, Ulrich Kück   +4 more
doaj   +1 more source

Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors

Stem Cell Reports, 2018
Summary: Adult neurogenesis is regulated by stem cell niche-derived extrinsic factors and cell-intrinsic regulators, yet the mechanisms by which niche signals impinge on the activity of intrinsic neurogenic transcription factors remain poorly defined ...
Jasmine Kolb, Marie Anders-Maurer, Tanja Müller, Ann-Christin Hau, Britta Moyo Grebbin, Wiebke Kallenborn-Gerhardt, Christian Behrends, Dorothea Schulte   +7 more
doaj   +1 more source

EF-P Posttranslational Modification Has Variable Impact on Polyproline Translation in Bacillus subtilis

mBio, 2018
Elongation factor P (EF-P) is a ubiquitous translation factor that facilitates translation of polyproline motifs. In order to perform this function, EF-P generally requires posttranslational modification (PTM) on a conserved residue.
Anne Witzky, Katherine R. Hummels, Rodney Tollerson, Andrei Rajkovic, Lisa A. Jones, Daniel B. Kearns, Michael Ibba   +6 more
doaj   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Posttranslational regulatory mechanism of PD-L1 in cancers and associated opportunities for novel small-molecule therapeutics

Acta Biochimica et Biophysica Sinica
Despite the tremendous progress in cancer research over the past few decades, effective therapeutic strategies are still urgently needed. Accumulating evidence suggests that immune checkpoints are the cause of tumor immune escape.
Cai Minchen, Xu Mengting, Yu Dianping, Wang Qun, Liu Sanhong   +4 more
doaj   +1 more source

Table 1. Posttranslational modification on titin.pdf

, 2019
titin posttranslational ...
henk granzier (6656115), coen ottenheijm (6656051), robbert van der pijl (6656114)   +2 more
core   +1 more source

Labeling and quantifying sites of protein palmitoylation

BioTechniques, 2004
As a reversible posttranslational modification, protein palmitoylation has the potential to regulate the trafficking and function of a variety of proteins. However, the extent, function, and dynamic nature of palmitoylation are poorly resolved because of
Renaldo C. Drisdel, William N. Green
doaj   +1 more source