Results 191 to 200 of about 71,707 (290)

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

A Versatile Method for Site-Specific Chemical Installation of Aromatic Posttranslational Modification Analogs into Proteins. [PDF]

J Am Chem Soc
Lin X, Mandal S, Nithun RV, Kolla R, Bouri B, Lashuel HA, Jbara M.   +6 more
europepmc   +1 more source

Unique Posttranslational Modification Sites of Acetylation, Citrullination, Glutarylation, and Phosphorylation Are Found to Be Specific to the Proteins Partitioned in the Triton X-114 Fractions of Leptospira. [PDF]

ACS Omega, 2022
Phukan H, Sarma A, Rex DAB, Rai AB, Prasad TSK, Madanan MG.   +5 more
europepmc   +1 more source

The U _S 3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins

, 2001
Joshua Munger, Bernard Roizman
openalex   +1 more source

A Biomarker‐Based Classification of Corticobasal Syndrome

Movement Disorders, EarlyView.
Abstract Background Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau‐predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer's disease (AD).
Carla Palleis, Alexander Maximilian Bernhardt, Endy Weidinger, Urban M. Fietzek, Alexander Jäck, Sabrina Katzdobler, Johannes Gnörich, Theresa Bauer, Nicolai Franzmeier, Robert Perneczky, German Imaging Initiative for Tauopathies (GII4T), Matthias Brendel, Johannes Levin, Günter U. Höglinger   +13 more
wiley   +1 more source

Estrogens Regulate Posttranslational Modification of Neural Cell Adhesion Molecule during the Estrogen-Induced Gonadotropin Surge [PDF]

, 2009
Orkun Tan, Ahmed Fadiel, Aimee S. Chang, Necdet Demir, Rachel Jeffrey, Tamas L. Horváth, Luis Miguel García‐Segura, Frederick Naftolin   +7 more
openalex   +1 more source

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

Medicinal Research Reviews, EarlyView.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg, Tracie Widjaja, Adriaan P. IJzerman, Daan van der Es   +3 more
wiley   +1 more source

Proteome, Lysine Acetylome, and Succinylome Identify Posttranslational Modification of STAT1 as a Novel Drug Target in Silicosis. [PDF]

Mol Cell Proteomics
Zhang T, Wang Y, Sun Y, Song M, Pang J, Wang M, Zhang Z, Yang P, Chen Y, Qi X, Zhou H, Han Z, Xing Y, Liu Y, Li B, Liu J, Yang J, Wang J.   +17 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Posttranslational Modification of Sox11 Regulates RGC Survival and Axon Regeneration. [PDF]

eNeuro, 2021
Chang KC, Bian M, Xia X, Madaan A, Sun C, Wang Q, Li L, Nahmou M, Noro T, Yokota S, Galvao J, Kreymerman A, Tanasa B, Hu Y, Goldberg JL.   +14 more
europepmc   +1 more source