Results 221 to 230 of about 120,482 (333)

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

A Versatile Method for Site-Specific Chemical Installation of Aromatic Posttranslational Modification Analogs into Proteins. [PDF]

J Am Chem Soc
Lin X, Mandal S, Nithun RV, Kolla R, Bouri B, Lashuel HA, Jbara M.   +6 more
europepmc   +1 more source

The competitive interplay of 12‐oxophytodienoic acid (OPDA), protein thiols, and glutathione

The FEBS Journal, EarlyView.
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Madita Knieper, Ruben Schwarz, Lara Vogelsang, Jens Sproß, Armağan Kaya, Maike Bittmann, Harald Gröger, Andrea Viehhauser, Karl‐Josef Dietz   +8 more
wiley   +1 more source

Recovery From Anorexia Nervosa: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Unique Posttranslational Modification Sites of Acetylation, Citrullination, Glutarylation, and Phosphorylation Are Found to Be Specific to the Proteins Partitioned in the Triton X-114 Fractions of Leptospira. [PDF]

ACS Omega, 2022
Phukan H, Sarma A, Rex DAB, Rai AB, Prasad TSK, Madanan MG.   +5 more
europepmc   +1 more source

30 Years of Enamel Matrix Derivative (EMD): Biological Foundations and Systematic Review With Meta‐Analyses Across Multiple Clinical Indications

Journal of Periodontal Research, EarlyView.
EMD is one of the few biological agents with human histologic evidence supporting periodontal regeneration. This is reflected in improved clinical outcomes when used in regenerative surgery for intrabony defects. Despite its biological plausibility for broader therapeutic applications, further high‐quality randomized clinical trials are needed to ...
Richard J. Miron, Nima Farshidfar, Yu‐Kang Tu, Chian‐Heng Su, Paras Ahmad, Nathan E. Estrin, Reinhard Gruber, Yoshinori Shirakata, Dieter D. Bosshardt, Mario Romandini, Anton Sculean   +10 more
wiley   +1 more source

Proteome, Lysine Acetylome, and Succinylome Identify Posttranslational Modification of STAT1 as a Novel Drug Target in Silicosis. [PDF]

Mol Cell Proteomics
Zhang T, Wang Y, Sun Y, Song M, Pang J, Wang M, Zhang Z, Yang P, Chen Y, Qi X, Zhou H, Han Z, Xing Y, Liu Y, Li B, Liu J, Yang J, Wang J.   +17 more
europepmc   +1 more source

Posttranslational Modification of Sox11 Regulates RGC Survival and Axon Regeneration. [PDF]

eNeuro, 2021
Chang KC, Bian M, Xia X, Madaan A, Sun C, Wang Q, Li L, Nahmou M, Noro T, Yokota S, Galvao J, Kreymerman A, Tanasa B, Hu Y, Goldberg JL.   +14 more
europepmc   +1 more source

Integrative Proteomic Analysis of Posttranslational Modification in The Inflammatory Response

, 2020
Feiyang Ji, Menghao Zhou, Huihui Zhu, Zhengyi Jiang, Qirui Li, Xiaoxi Ouyang, Yiming Lv, Sainan Zhang, Tian Wu, Lanjuan Li   +9 more
openalex   +1 more source

Nonallosteric activation of posttranslational modification enzymes by active site-directed inhibitors. [PDF]

Comput Struct Biotechnol J
Pesaresi A.
europepmc   +1 more source