Protein Target Highlights in CASP16: Insights From the Structure Providers
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT This article presents an in‐depth analysis of selected CASP16 targets, with a focus on their biological and functional significance. The authors highlight the most relevant features of the target proteins and discuss how well these were reproduced in the submitted predictions.
Leila T. Alexander +34 more
wiley +1 more source
Modulation of Erythrocyte Membrane Mechanical Properties by Posttranslational Modifications
, 2007 Sumie Manno, Yuichi Takakuwa
openalex +2 more sources
The role of posttranslational modifications in the assembly of stress granules [PDF]
, 2010 Takbum Ohn, Paul Anderson
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Assessment of Pharmaceutical Protein–Ligand Pose and Affinity Predictions in CASP16
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The protein–ligand component of the 16th Critical Assessment of Structure Prediction (CASP16) challenged participants to predict both binding poses and affinities of small molecules to protein targets, with a focus on drug‐like compounds from pharmaceutical discovery projects. Thirty research groups submitted predictions for 229 protein–ligand
Michael K. Gilson +5 more
wiley +1 more source
Specific posttranslational modification regulates early events in mammary carcinoma formation [PDF]
, 2010 Hua‐Bei Guo +5 more
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The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)–like 2 [PDF]
, 2011 Anne M. Fitzpatrick +8 more
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Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Insect Science, EarlyView.Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source