The post-translational modification landscape of commercial beers
Scientific Reports, 2021 Beer is one of the most popular beverages worldwide. As a product of variable agricultural ingredients and processes, beer has high molecular complexity.
Edward D. Kerr +8 more
doaj +1 more source
Carbon Dioxide and the Carbamate Post-Translational Modification
Frontiers in Molecular Biosciences, 2022 Carbon dioxide is essential for life. It is at the beginning of every life process as a substrate of photosynthesis. It is at the end of every life process as the product of post-mortem decay.
Lynsay I. Blake, Martin J. Cann
doaj +1 more source
Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2
Advanced Science, EarlyView.Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang +15 more
wiley +1 more source
Labeling Proteins with Small Molecules by Site-Specific Posttranslational Modification
, 2016 We report here the development of a general strategy for site-specific labeling of proteins with small molecules by posttranslational modification enzyme, phosphopantetheinyl transferase Sfp.
Jun Yin (94374) +3 more
core +1 more source
Research Article Posttranslational Protein Modification in the Salivary Glands of Sjögren’s Syndrome Patients [PDF]
, 2013 Copyright © 2013 Rafael Herrera-Esparza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
Martha Adriana Badillo-soto +15 more
core +1 more source
Advanced Science, EarlyView.Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen +4 more
wiley +1 more source
Taking the Occam’s Razor Approach to Hedgehog Lipidation and Its Role in Development
Journal of Developmental Biology, 2018 All Hedgehog (Hh) proteins signal from producing cells to distant receiving cells despite being synthesized as N-and C-terminally lipidated, membrane-tethered molecules.
Dominique Manikowski +2 more
doaj +1 more source
Purification and properties of glyceraldehyde-3-phosphate dehydrogenase from the skeletal muscle of the hibernating ground squirrel, Ictidomys tridecemlineatus [PDF]
PeerJ, 2014 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the skeletal muscle of euthermic and torpid Ictidomys tridecemlineatus was purified to electrophoretic homogeneity using a novel method involving Blue-agarose and Phenyl-agarose chromatography ...
Ryan A.V. Bell +2 more
doaj +2 more sources
Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism. [PDF]
, 2011 BACKGROUND: Human cancers consume larger amounts of glucose compared to normal tissues with most being converted and excreted as lactate despite abundant oxygen availability (Warburg effect).
Andreja Šmerc +5 more
core +1 more source
Chiral Posttranslational Modification to Lysine epsilon-Amino Groups [PDF]
, 2022 The sophistication of proteomic analysis has revealed that protein lysine residues are posttranslationally modified by a variety of acyl groups. Protein lysine acetylation regulates metabolism, gene expression, and microtubule formation and has been ...
Michael, Bæk +7 more
core +1 more source