Results 111 to 120 of about 15,278 (270)

Muscarinic Modulation of High Frequency Oscillations in Pedunculopontine Neurons [PDF]

open access: yes, 2013
We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as ...
Belen Goitia   +5 more
core   +2 more sources

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

open access: yesAdvanced Materials Interfaces, EarlyView.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido   +6 more
wiley   +1 more source

Vonoprazan-based therapy for eradication: experience and clinical evidence

open access: yesTherapeutic Advances in Gastroenterology, 2016
Stable suppression of gastric acid secretion is a crucial factor in Helicobacter pylori eradication. Vonoprazan is a potassium-competitive acid blocker recently approved for use in Japan.
Yuko Akazawa   +2 more
doaj   +1 more source

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]

open access: yes, 2017
Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M.   +17 more
core   +2 more sources

Graphene‐Interfaced Stretchable Sweat Patch for Multiplexed Electrochemical Monitoring of IL‐6, Glucose, and Calcium Ions

open access: yesAdvanced Materials Technologies, EarlyView.
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon   +4 more
wiley   +1 more source

RGS4 regulates partial agonism of the M2 muscarinic receptor-activated K+ currents. [PDF]

open access: yes, 2014
Partial agonists are used clinically to avoid overstimulation of receptor-mediated signalling, as they produce a submaximal response even at 100% receptor occupancy.
Chen, I-Shan   +3 more
core   +2 more sources

In Situ Photopolymerization of Smectic B Liquid‐Crystalline Electrolytes from Mesogenic Phosphate–Diacrylate/Ionic Liquid Complexes for High‐Performance Soft Ionic Actuators

open access: yesAdvanced Robotics Research, EarlyView.
A flexible liquid‐crystalline electrolyte membrane via in situ photopolymerization of a phosphate‐functionalized mesogen, ionic liquid, and diacrylate monomer is developed. The resulting smectic B (SmB)‐phase structure enables 2D ion transport with high conductivity (10−4 S cm−1).
Chengyang Liu, Masafumi Yoshio
wiley   +1 more source

Research progress of potassium-competitive acid blockers in the treatment of Helicobacter pylori

open access: yesAnnals of Medicine
Helicobacter pylori (H. pylori) infection is a primary pathogen responsible for gastrointestinal diseases, including gastritis, peptic ulcer disease, and gastric cancer. Therefore, the eradication of H.
Zhaoli Ma   +3 more
doaj   +1 more source

Vonoprazan treatment improves gastrointestinal symptoms in patients with gastroesophageal reflux disease

open access: yesKaohsiung Journal of Medical Sciences, 2017
The effects of vonoprazan, a new potassium-competitive acid blocker, on gastroesophageal reflux disease (GERD) symptom are not fully elucidated. The aim of this study is to determine the effect of vonoprazan on GERD and associated gastrointestinal ...
Satoshi Shinozaki   +6 more
doaj   +1 more source

Arachidonic acid reduces the stress response of gilthead seabream Sparus aurata L [PDF]

open access: yes, 2004
Contains fulltext : 13883.pdf ( ) (Open ...
Anholt, R.D. van   +4 more
core   +4 more sources

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