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[Vonoprazan: a novel potassium-competitive acid blocker].
Nihon rinsho. Japanese journal of clinical medicine, 2015A potent, rapid acting potassium-competitive acid blocker, vonoprazan, is introduced for clinical use in Japan. A number of phase III clinical trials comparing the efficacy of vonoprazan with lansoprazole, showed non-inferior or superior effectiveness in a spectrum of acid-related diseases.
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Vonoprazan: A Revolutionary Potassium-Competitive Acid Blocker in Gastroenterology
Vonoprazan, a novel potassium-competitive acid blocker (P-CAB) that is emerging as a new alternative among conventional proton pump inhibitors (PPIs) for treating acid-related gastrointestinal disorders. Review vonoprazan's pharmacological details, its excellent ability to suppress acid secretion, and such clinical aspects as gastroesophageal reflux ...openaire +1 more source
Eradication of Helicobacter pylori by a potassium-competitive acid blocker alone?
Scandinavian Journal of GastroenterologyHelicobacter pylori (H. pylori), the dominating cause of gastric cancer, most often infects children initiating inflammation in the antral part and spreads orally to the oxyntic mucosa. Traditionally, eradication of H. pylori has been based upon a combination of antibiotics together with a proton pump inhibitor (PPI) to reduce gastric destruction of ...
Helge Waldum, Reidar Fossmark
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Tegoprazan is a potassium-competitive blocker of hydrochloric acid secretion
Experimental and Clinical GastroenterologyPotassium-competitive acid blockers (P-CABs), such as tegoprazan, are a new class of drugs that can completely block the potassium-binding site of the gastric H+/K+ ATPase, potentially overcoming the limitations of proton pump inhibitors (PPIs). Tegoprazan was developed by CJ Healthcare (Republic of Korea) for the treatment of gastroesophageal reflux ...
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Gastric candidiasis developing after administration of potassium-competitive acid blocker
Gastrointestinal Endoscopy, 2019Seiya, Kato +4 more
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