Results 211 to 220 of about 193,403 (262)

Systemic Glucose Homeostasis Requires Pancreatic but Not Neuronal ATP-sensitive Potassium Channels. [PDF]

Function (Oxf)
Li AH, Tsai WS, Tsai WH, Yang SB.
europepmc   +1 more source

Vasorelaxant effects of 3-methoxycatechol are not via direct activation of voltage-gated potassium channels. [PDF]

Vascul Pharmacol
Manville RW, Baldwin SN, Schaub OH, Jepps TA, Abbott GW.   +4 more
europepmc   +1 more source

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Lysosomal Potassium Channels

Cell Calcium, 2022
Lysosomes are acidic membrane-bound organelles that use hydrolytic enzymes to break down material through pathways such as endocytosis, phagocytosis, mitophagy, and autophagy. To function properly, intralysosomal environments are strictly controlled by a set of integral membrane proteins such as ion channels and transporters.
Peng, Huang, Mengnan, Xu, Yi, Wu, Alia Kazim, Rizvi Syeda, Xian-Ping, Dong   +4 more
openaire   +4 more sources

Mitochondrial potassium channels

IUBMB Life, 2009
AbstractMitochondrial potassium channels are believed to contribute to cytoprotection of injured cardiac and neuronal tissues. The following potassium channels have been described in the inner mitochondrial membrane: the ATP‐regulated potassium channel, the large conductance Ca2+‐activated potassium channel, the voltage‐gated Kv1.3 potassium channel ...
Adam Szewczyk, Wieslawa Jarmuszkiewicz, Wolfram S Kunz   +2 more
exaly   +3 more sources

Potassium channels and epilepsy

Acta Neurologica Scandinavica, 2022
With the development and application of next-generation sequencing technology, the aetiological diagnosis of genetic epilepsy is rapidly becoming easier and less expensive. Additionally, there is a growing body of research into precision therapy based on genetic diagnosis.
Kai, Gao, Zehong, Lin, Sijia, Wen, Yuwu, Jiang   +3 more
openaire   +2 more sources

Potassium Channels in Cancer

2021
Neoplastic transformation is reportedly associated with alterations of the potassium transport across plasma and intracellular membranes. These alterations have been identified as crucial elements of the tumourigenic reprogramming of cells. Potassium channels may contribute to cancer initiation, malignant progression and therapy resistance of tumour ...
Katrin, Ganser, Lukas, Klumpp, Helmut, Bischof, Robert, Lukowski, Franziska, Eckert, Stephan M, Huber   +5 more
openaire   +2 more sources

Potassium Channels

IEEE Transactions on Nanobioscience, 2005
Potassium channels are integral membrane proteins that selectively transport K+ across the cell membrane. They are present in all mammalian cells and have a wide variety of roles in both excitable and nonexcitable cells. The phenotypic diversity required to accomplish their various roles is created by differences in conductance, the timecourse and ...
Stephen J, Korn, Josef G, Trapani
openaire   +2 more sources

Trafficking of potassium channels

Current Opinion in Neurobiology, 2005
Recent progress in our understanding of the trafficking of potassium channels can be seen in particular when considering the Kv-type channels. To date, we have discovered that folding of the Kv1.3 T1 domain begins in the ribosomal exit tunnel, and that the cell surface expression of Kv4 channels is enhanced by the presence of two recently identified ...
Heusser, Katja, Schwappach, Blanche
openaire   +3 more sources

Pharmacology of Potassium Channels

1997
Publisher Summary Potassium channels represent the largest and most diverse family of ion channels. K+ channels can be divided into two groups, voltage-gated and ligand-gated channels, depending on the stimulus that triggers the conformational changes leading to channel opening. K+ channels share in common the feature of having high selectivity for K+
M L, Garcia, M, Hanner, H G, Knaus, R, Koch, W, Schmalhofer, R S, Slaughter, G J, Kaczorowski   +6 more
openaire   +2 more sources