Results 81 to 90 of about 3,077,235 (395)

Unique features of two potassium channels, OsKAT2 and OsKAT3, expressed in rice guard cells. [PDF]

PLoS ONE, 2013
Potassium is the most abundant cation and a myriad of transporters regulate K(+) homeostasis in plant. Potassium plays a role as a major osmolyte to regulate stomatal movements that control water utility of land plants.
Hyunsik Hwang, Jinyoung Yoon, Hyun Yeong Kim, Myung Ki Min, Jin-Ae Kim, Eun-Hye Choi, Wenzhi Lan, Young-Min Bae, Sheng Luan, Hana Cho, Beom-Gi Kim   +10 more
doaj   +1 more source

Altered calcium influx of peripheral Th2 cells in pediatric Crohn’s disease: infliximab may normalize activation patterns [PDF]

, 2016
OBJECTIVE: Crohn's disease is a chronic inflammation of the gastrointestinal tract with an abnormal immune phenotype. We investigated how intracellular calcium kinetics of Th1 and Th2 lymphocytes alter upon specific inhibition of Kv1.3 and IKCa1 ...
Ardid, Brand, Cahalan, Dubinsky, Feske, Gascan, Glimcher, Griffiths, Hansen, Kruidenier, Köhler, Oh-hora, Sartor, Skolnik, Toldi, Toldi, Toldi, Treszl, Treszl, Vasarhelyi, Vasarhelyi, Vasarhelyi, Veres, Volk, Weiss   +24 more
core   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Clofilium inhibits Slick and Slack potassium channels

Biologics: Targets & Therapy, 2012
Maria de los Angeles Tejada,1 Kathleen Stolpe,1 Anne-Kristine Meinild,2 Dan A Klaerke11Department of Physiology and Biochemistry, Faculty of Life Sciences, 2Institute of Biology, Faculty of Science, University of Copenhagen, Copenhagen, DenmarkAbstract ...
Tejada MA, Stolpe K, Meinild AK, Klaerke DA   +3 more
doaj  

VKCDB: Voltage-gated potassium channel database

BMC Bioinformatics, 2004
Background The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based component of the membrane potential and are thus central to many critical ...
Gallin Warren J, Li Bin
doaj   +1 more source

Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice [PDF]

, 2019
Potassium (K+) channels shape the response properties of neurons. Although enormous progress has been made to characterize K+ channels in the primary auditory neurons, the molecular identities of many of these channels and their contributions to hearing ...
Gratton, Michael Anne, Jones, Sherri M., Jones, Timothy A., Lee, Jeong Han, Park, Seojin, Pyott, Sonja J., Reijntjes, Daniël O. J., Schubert, Nick M. A., van Tuinen, Marcel, Vijayakumar, Sarath, Xia, Xiao-Ming, Yamoah, Ebenezer N.   +11 more
core   +5 more sources

Calcium-activated potassium channels

Current Opinion in Neurobiology, 1998
Calcium-activated potassium channels are fundamental regulators of neuronal excitability, participating in interspike interval and spike-frequency adaptation. For large-conductance calcium-activated potassium (BK) channels, recent experiments have illuminated the fundamental biophysical mechanisms of gating, demonstrating that BK channels are voltage ...
Vergara Montecinos, Cecilia, Latorre, Ramón, Marrion, Neil V., Adelman, John P.   +3 more
openaire   +3 more sources

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Potassium channel clustering: mechanisms shaping axonal excitability

Frontiers in Cellular Neuroscience
The precise clustering of ion channels at axon initial segments (AIS) and nodes of Ranvier is essential for axonal excitability and rapid action potential propagation.
Gabriel Escobedo, Matthew N. Rasband
doaj   +1 more source

Role of Astrocytic Inwardly Rectifying Potassium (Kir) 4.1 Channels in Epileptogenesis

Frontiers in Neurology, 2020
Astrocytes regulate potassium and glutamate homeostasis via inwardly rectifying potassium (Kir) 4.1 channels in synapses, maintaining normal neural excitability.
Masato Kinboshi, Masato Kinboshi, Akio Ikeda, Yukihiro Ohno   +3 more
doaj   +1 more source