Results 61 to 70 of about 355,939 (300)

Ultrasound Stimulation Modulates Voltage-Gated Potassium Currents Associated With Action Potential Shape in Hippocampal CA1 Pyramidal Neurons

Frontiers in Pharmacology, 2019
Potassium channels (K+) play an important role in the regulation of cellular signaling. Dysfunction of potassium channels is associated with several severe ion channels diseases, such as long QT syndrome, episodic ataxia and epilepsy.
Zhengrong Lin, Xiaowei Huang, Wei Zhou, Wenjun Zhang, Wenjun Zhang, Yingzhe Liu, Yingzhe Liu, Tianyuan Bian, Tianyuan Bian, Lili Niu, Long Meng, Yanwu Guo   +11 more
doaj   +1 more source

Altered calcium influx of peripheral Th2 cells in pediatric Crohn’s disease: infliximab may normalize activation patterns [PDF]

, 2016
OBJECTIVE: Crohn's disease is a chronic inflammation of the gastrointestinal tract with an abnormal immune phenotype. We investigated how intracellular calcium kinetics of Th1 and Th2 lymphocytes alter upon specific inhibition of Kv1.3 and IKCa1 ...
Ardid, Brand, Cahalan, Dubinsky, Feske, Gascan, Glimcher, Griffiths, Hansen, Kruidenier, Köhler, Oh-hora, Sartor, Skolnik, Toldi, Toldi, Toldi, Treszl, Treszl, Vasarhelyi, Vasarhelyi, Vasarhelyi, Veres, Volk, Weiss   +24 more
core   +1 more source

Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions

Advanced Functional Materials, EarlyView.
This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian, Jingkai Lin, Zhihao Tian, Selusiwe Ncube, Huayang Zhang, Emiliano Cortés, Hongqi Sun, Shaobin Wang   +7 more
wiley   +1 more source

Potassium channel‐mediated NO‐induced vasodilation during maturation: Dominance of Kv7 channels

FASEB BioAdvances
Maturation represents a process characterized by adaptive changes, particularly in the circulatory system. However, it is not known whether, in neonates, potassium channels contribute to NO‐induced vasorelaxation at all and, if so, which potassium ...
Anastasia A. Shvetsova, Dina K. Gaynullina, Peter Winkler, Paulus Wohlfart, Rudolf Schubert   +4 more
doaj   +1 more source

Migraine is a dysfunction of neuronal potassium ion channels

Frontiers in Neurology
Migraine is a primary headache disorder characterized by unilateral pain usually with aura, that affects approximately one in six individuals in India.
Girishwaran M., S. Sajitha Lulu
doaj   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source

Potassium channels in C. elegans [PDF]

, 2005
Ion channels are the "transistors" (electronic switches) of the brain that generate and propagate electrical signals in the aqueous environment of the brain and nervous system. Potassium channels are particularly important because, not only do they shape
Baban, Beravan, Butler, Alice, Fawcett, Gloria L, Ferreira, Gonzalo, Salkoff, Lawrence B, Santi, Celia M, Wei, Aguan   +6 more
core   +2 more sources

SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement

Advanced Functional Materials, EarlyView.
An enzyme‐catalyzed surface‐initiated atom transfer radical polymerization (SI‐bioATRP) of an anionic monomer within mesoporous silica particles, using hemoglobin as a catalyst, allows for controlling the location of the formed polymer via size‐exclusion effects between the nanopores and the biomacromolecules, thereby opening routes to functional ...
Oleksandr Wondra, Eleonora Ornati, Robert Lehn, Joanna J. Mikolei, Hergen Breitzke, Raheleh Pardehkhorram, Gerd Buntkowsky, Nico Bruns, Annette Andrieu‐Brunsen   +8 more
wiley   +1 more source

K2P channels and their protein partners. [PDF]

, 2005
A decade since their discovery, the K2P channels are recognized as pathways dedicated to regulated background leakage of potassium ions that serve to control neuronal excitability. The recent identification of protein partners that directly interact with
Goldstein, Steve AN, Plant, Leigh D, Rajan, Sindhu   +2 more
core   +1 more source

Overexpression of Large-Conductance Calcium-Activated Potassium Channels in Human Glioblastoma Stem-Like Cells and Their Role in Cell Migration [PDF]

, 2017
Glioblastomas (GBMs) are brain tumors characterized by diffuse invasion of cancer cells into the healthy brain parenchyma, and establishment of secondary foci. GBM cells abundantly express large-conductance, calcium-activated potassium (BK) channels that
Abdullaev, Bao, Bednarczyk, Beier, Brenner, Brescia, Buttigieg, Calogero, Catacuzzeno, Catacuzzeno, Catacuzzeno, Catacuzzeno, Chen, Choy, Cuddapah, Eckel-Passow, Edalat, Eskandari, Fioretti, Fioretti, Gu, Holland, Inoue, Kyle, Liu, Maher, Maugeri-Saccà, Maugeri-Saccà, McFerrin, Meera, Park, Ransom, Ruggieri, Sforna, Sforna, Shruti, Siemen, Sontheimer, Soria, Soroceanu, Steinle, Torres, Turner, Wang, Weaver, Weiger, Wondergem, Wu, Yu, Zhang   +49 more
core   +1 more source