Results 31 to 40 of about 21,570,093 (257)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Presence and Distribution of Economically Important Potato Viruses in Montenegro [PDF]

open access: yesPesticidi i Fitomedicina, 2011
The research was carried out, in the period 2002-2004 in order to determine the presence and distribution of potato viruses at 12 different locations and on 9 different potato varieties grown in Montenegro.
Jelena Zindović
doaj  

Screening of potato breedung lines for the potato virus Y resistance genes Rychc and Ryadg

open access: yesКарантин і захист рослин, 2023
Goal. Molecular identification of carriers of the potato virus Y (PVY) resistance genes Rychc and Ryadg among potato lines of the Polissia Research Station of the Institute of Potato Growing of the National Academy of Agrarian Sciences of Ukraine ...
S. Kyrychenko, N. Kozub
doaj   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

One-step real-time multiplex reverse transcription-polymerase chain reaction assay with melt curve analysis for detection of potato leafroll virus, potato virus S, potato virus X, and potato virus Y

open access: yesVirology Journal, 2021
Background Certification of seed potato as free of viruses is essential for stable potato production. Among more than 30 virus species infecting potato, potato leafroll virus (PLRV), potato virus S (PVS), potato virus X (PVX), and potato virus Y (PVY ...
Nobuya Onozuka   +3 more
doaj   +1 more source

Evidence that a component other than virus particle is needed for aphid transmission of potato virus Y

open access: yes, 1974
Aphids (Myzus persicae Sulz) did not transmit potato virus Y after probing into purified virus preparations, but did if these preparations were first mixed with extracts of infected plants from which all potato virus Y particles had been removed by ...
Kassanis, B., Govier, D. A.
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Prevalence of potato viruses on potato (Solanum tuberosum L.) grown in the Western Highlands of Cameroon

open access: yesJournal of Agriculture and Food Research, 2021
Solanum tuberosum L. is considered by the Food and Agricultural Organization as one of the alternative food crops that can help to fight against hunger in the world.
Dély Carlos Temfack Deloko   +6 more
doaj   +1 more source

The behaviour of some naturally occurring strains of potato virus y

open access: yes, 1947
Potato virus Y was obtained from field crops of potatoes in many strains which differed widely in virulence and caused diseases in the variety Majestic ranging from severe leaf-drop streak to mild mosaic.
Kassanis, B., Bawden, F. C.
core   +1 more source

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