Results 1 to 10 of about 1,009,444 (403)

Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes [PDF]

open access: yes, 2014
Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster.
Biggin, P   +5 more
core   +9 more sources

Preparation and the assessed efficacy of oral baits for the vaccination of free-roaming dogs against rabies [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Rabies is considered a highly fatal zoonotic disease and many deaths in humans have been associated with dog bites. This study was designed to prepare an oral anti-rabies vaccine in the form of baits to eliminate the disease in free ...
Naglaa I. Aly   +7 more
doaj   +1 more source

New Modified Recombinant Botulinum Neurotoxin Type F with Enhanced Potency

open access: yesToxins, 2021
Botulinum neurotoxins (BoNTs) are notorious toxins and powerful agents and can be lethal, causing botulism, but they are also widely used as therapeutics, particularly to treat neuromuscular disorders.
David Burgin   +9 more
doaj   +1 more source

Practical Application of Novel Test Methods to Evaluate the Potency of Botulinum Toxin: A Comparison Analysis among Widely Used Products in Korea

open access: yesToxins, 2021
The safe and effective dosing of botulinum neurotoxins (BoNTs) requires accurate and reliable methods to measure their potency. Several novel methods have been introduced over the past decade; however, only few studies have compared the potency of BoNT ...
Ji-Yeon Hong   +4 more
doaj   +1 more source

The First WHO International Standard for Adalimumab: Dual Role in Bioactivity and Therapeutic Drug Monitoring

open access: yesFrontiers in Immunology, 2021
The expanded availability of adalimumab products continues to widen patient access and reduce costs with substantial benefit to healthcare systems.
Meenu Wadhwa   +4 more
doaj   +1 more source

Nerve-Sparing Cryoablation for the Treatment of Primary Prostate Cancer: the Preliminary Report [PDF]

open access: yesKosin Medical Journal, 2014
Background: To present a pilot study of nerve-sparing cryoablation for the treatment of primary prostate cancer. Materials and Methods: Between 2008 and 2011, 9 patients underwent nerve-sparing cryoablation (unilateral 5, bilateral 4 patients).
Seong Choi
doaj   +1 more source

Potency of Veterinary Rabies Vaccines Marketed in Sri Lanka

open access: yesVaccines, 2023
Seven brands of veterinary rabies vaccines are commercially available in Sri Lanka, but there is no established procedure to test the potency of the vaccines at the local level, especially prior to their release.
Hasanthi Rathnadiwakara   +5 more
doaj   +1 more source

Are Potency and Actuality Compatible in Aristotle? [PDF]

open access: yes, 2018
The belief that Aristotle opposes potency (dunamis) to actuality (energeia or entelecheia) has gone untested. This essay defines and distinguishes forms of the Opposition Hypothesis—the Actualization, Privation, and Modal—examining the texts and ...
Sentesy, Mark
core   +1 more source

Frequency and Severity of Neutropenia Associated with Food and Drug Administration Approved and Compounded Formulations of Lomustine in Dogs with Cancer. [PDF]

open access: yes, 2015
BackgroundCompounded lomustine is used commonly in veterinary patients. However, the potential variability in these formulations is unknown and concern exists that compounded formulations of drugs may differ in potency from Food and Drug Administration ...
Burton, JH   +5 more
core   +2 more sources

Limited Potential or Unfavorable Manipulations? Strategies Toward Efficient Mesenchymal Stem/Stromal Cell Applications

open access: yesFrontiers in Cell and Developmental Biology, 2020
Despite almost 50 years of research and over 20 years of preclinical and clinical studies, the question of curative potential of mesenchymal stem/stromal cells (MSCs) is still widely discussed in the scientific community.
Antonina Lavrentieva   +2 more
doaj   +1 more source

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