Results 1 to 10 of about 396,791 (317)

New Modified Recombinant Botulinum Neurotoxin Type F with Enhanced Potency

open access: yesToxins, 2021
Botulinum neurotoxins (BoNTs) are notorious toxins and powerful agents and can be lethal, causing botulism, but they are also widely used as therapeutics, particularly to treat neuromuscular disorders.
David Burgin   +9 more
doaj   +1 more source

Practical Application of Novel Test Methods to Evaluate the Potency of Botulinum Toxin: A Comparison Analysis among Widely Used Products in Korea

open access: yesToxins, 2021
The safe and effective dosing of botulinum neurotoxins (BoNTs) requires accurate and reliable methods to measure their potency. Several novel methods have been introduced over the past decade; however, only few studies have compared the potency of BoNT ...
Ji-Yeon Hong   +4 more
doaj   +1 more source

The First WHO International Standard for Adalimumab: Dual Role in Bioactivity and Therapeutic Drug Monitoring

open access: yesFrontiers in Immunology, 2021
The expanded availability of adalimumab products continues to widen patient access and reduce costs with substantial benefit to healthcare systems.
Meenu Wadhwa   +4 more
doaj   +1 more source

Nerve-Sparing Cryoablation for the Treatment of Primary Prostate Cancer: the Preliminary Report [PDF]

open access: yesKosin Medical Journal, 2014
Background: To present a pilot study of nerve-sparing cryoablation for the treatment of primary prostate cancer. Materials and Methods: Between 2008 and 2011, 9 patients underwent nerve-sparing cryoablation (unilateral 5, bilateral 4 patients).
Seong Choi
doaj   +1 more source

Potency of Veterinary Rabies Vaccines Marketed in Sri Lanka

open access: yesVaccines, 2023
Seven brands of veterinary rabies vaccines are commercially available in Sri Lanka, but there is no established procedure to test the potency of the vaccines at the local level, especially prior to their release.
Hasanthi Rathnadiwakara   +5 more
doaj   +1 more source

Preparation and the assessed efficacy of oral baits for the vaccination of free-roaming dogs against rabies [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Rabies is considered a highly fatal zoonotic disease and many deaths in humans have been associated with dog bites. This study was designed to prepare an oral anti-rabies vaccine in the form of baits to eliminate the disease in free ...
Naglaa I. Aly   +7 more
doaj   +1 more source

Durkheim’s totemic principle, shamanism and Southern African San religions

open access: yesHTS Teologiese Studies/Theological Studies, 2021
The study reappraised Emile Durkheim’s totemic principle in relation to the origins of religion and culture, using, amongst others, speech act theory and recent southern African epistemologies, especially David Lewis-Williams’ theory of shamanism ...
Richard A. Northover
doaj   +1 more source

Limited Potential or Unfavorable Manipulations? Strategies Toward Efficient Mesenchymal Stem/Stromal Cell Applications

open access: yesFrontiers in Cell and Developmental Biology, 2020
Despite almost 50 years of research and over 20 years of preclinical and clinical studies, the question of curative potential of mesenchymal stem/stromal cells (MSCs) is still widely discussed in the scientific community.
Antonina Lavrentieva   +2 more
doaj   +1 more source

Distribution and the potential growth of ganitri ( Elaeocarpus ganitrus Roxb ) in Central Java

open access: yesJurnal Ilmu Kehutanan, 2014
Ganitri (Elaeocarpus ganitrus Roxb) is a multi-purpose species that has the potential to be developed. This species has been known and cultivated by people, particularly in the region of Central Java.
Asep Rohandi, Gunawan Gunawan
doaj   +1 more source

Development and Qualification of an Antigen Integrity Assay for a Plasmodium falciparum Malaria Transmission Blocking Vaccine Candidate, Pfs230

open access: yesVaccines, 2022
During development of a subunit vaccine, monitoring integrity of the recombinant protein for process development and quality control is critical. Pfs230 is a leading malaria transmission blocking vaccine candidate and the first to reach a Phase 2 ...
Kazutoyo Miura   +9 more
doaj   +1 more source

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