Results 11 to 20 of about 396,791 (317)

Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors

Molecular Therapy: Methods & Clinical Development, 2020
Different approaches are used in the production of recombinant adeno-associated virus (rAAV). The two leading approaches are transiently transfected human HEK293 cells and live baculovirus infection of Spodoptera frugiperda (Sf9) insect cells ...
Neil G. Rumachik, Stacy A. Malaker, Nicole Poweleit, Lucy H. Maynard, Christopher M. Adams, Ryan D. Leib, Giana Cirolia, Dennis Thomas, Susan Stamnes, Kathleen Holt, Patrick Sinn, Andrew P. May, Nicole K. Paulk   +12 more
doaj   +1 more source

Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Frontiers in Pharmacology, 2021
Effective, safe, and pharmacokinetically suitable drugs are urgently needed to curb the ongoing COVID-19 pandemic. The main protease or 3C-like protease (Mpro or 3CLpro) of SARS-CoV-2 is considered an important target to formulate potent drugs ...
Hylemariam Mihiretie Mengist, Hylemariam Mihiretie Mengist, Hylemariam Mihiretie Mengist, Daniel Mekonnen, Daniel Mekonnen, Ahmed Mohammed, Ronghua Shi, Tengchuan Jin, Tengchuan Jin, Tengchuan Jin   +9 more
doaj   +1 more source

Ichthyofauna of Merbau River, Leuser Ecosystem Area, Indonesia: species composition, diversity, biometric condition, potency, and conservation status

The European Zoological Journal, 2023
The Leuser Ecosystem Area (LEA) is one of the largest conservation areas in Southeast Asia. However, the explorations of ichthyofauna at LEA are still relatively scarce compared to other vertebrates fauna.
M. Hidayat, S. Maulizar, A. S. Batubara, N. Kautsari, H. Latuconsina, F. M. Nur, I. Zulfahmi   +6 more
doaj   +1 more source

Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages

Frontiers in Immunology, 2022
Human Mesenchymal Stromal Cells (hMSCs) are a promising source for cell-based therapies. Yet, transition to phase III and IV clinical trials is remarkably slow.
Hélène Willer, Hélène Willer, Gabriele Spohn, Kimberly Morgenroth, Corinna Thielemann, Susanne Elvers-Hornung, Peter Bugert, Bruno Delorme, Melanie Giesen, Thomas Schmitz-Rixen, Erhard Seifried, Christiane Pfarrer, Richard Schäfer, Richard Schäfer, Richard Schäfer, Karen Bieback, Karen Bieback, Karen Bieback   +17 more
doaj   +1 more source

The Buddhist–Medical Interface in Tibet: Black Pill Traditions in Transformation

Religions, 2019
This paper introduces Tibetan pill traditions and examines two exceptional pill formulas that emerged from an early Buddhist–medical interface in Tibet, but followed different trajectories due to the increased specialization of religious and ...
Barbara Gerke
doaj   +1 more source

Mini review on Potency Evaluation of Rabies Vaccine preparations

Archives of Pharmaceutical Sciences Ain Shams University, 2021
Rabies is considered one of the most harmful viral infections of warm-blooded animals still. Thousands of people are infected with it each year worldwide. It is a fatal disease unless early treatment is received before the appearance of symptoms.
Walaa Rashed, Khaled M. Aboshanab, Mohammad M. Aboulwafa   +2 more
doaj   +1 more source

A Novel Approach to Assess the Potency of Topical Corticosteroids

Pharmaceutics, 2021
The potencies of topical corticosteroid products have mainly been classified using clinical data but in some instances, the US Food and Drug Administration’s (FDA’s) vasoconstrictor assay (VCA) to assess the skin blanching response has also been used ...
Michael Zvidzayi, Seeprarani Rath, Charles Bon, Sagaran Abboo, Isadore Kanfer   +4 more
doaj   +1 more source

The Human Penile Fibro-Vascular Assembly Requires the Integrity of Ten Fibro-Ligaments

Life
Introduction: Penile fibro-ligaments have been extensively studied for many centuries; however, there is, unfortunately, a lack of thorough understanding. We aimed to bridge the research gap between anatomy and surgical reconstruction.
Heng-Shuen Chen, Chu-Wen Fang, Raymond W. M. Tsai, Chih-Yuan Hsu, Geng-Long Hsu, Hsiu-Chen Lu, Mang-Hung Tsai, Jeff S. C. Chueh   +7 more
doaj   +1 more source

DIVERSITY AND POTENTIAL UTILIZATION OF SOME WILD MACROSCOPIC FUNGI AROUND IPB UNIVERSITY CAMPUS BUILDING

Jurnal Pendidikan Matematika dan IPA, 2020
Mushroom are cosmopolitan organisms which can emerge in a variety of environment, and around the university building is no exception.The goal of this study was to collect information on macrofungi diversity around IPB Unversity Campus Building in order ...
Ivan Permana Putra
doaj   +1 more source

Emergent Penile Venous Stripping for Treating Adolescent Impotence

Life
Introduction: Traditional anatomy-based penile venous surgery is deemed inadequate. Based on revolutionary insights into penile vasculature, penile venous stripping (PVS) shows promise in treating adolescent erectile dysfunction (AED). We aimed to report
Ko-Shih Chang, Yi-Kai Chang, Cho-Hsing Chung, Geng-Long Hsu, Jeff SC Chueh   +4 more
doaj   +1 more source