Results 251 to 260 of about 583,846 (360)

Quantifying human sweetness perception via a TAS1R2/TAS1R3-based model-predicted sweetness score. [PDF]

Food Chem X
Kim A, Kim Y, Choi N, Lee J, Kim MJ.
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Structural and Functional Basis for Biased Agonism at the 5-hydroxytryptamine 5A Receptor. [PDF]

Mol Biomed
Zhang X, Xie L, Chen P, Yu J, Tian X, Wang L, Wei J, Shao Z, Yan W, Xu Z.   +9 more
europepmc   +1 more source

Therapeutic potency and possible mechanism of Wuhu decoction underlying asthmatic progression via Th1/Th2 imbalance

Yan Hu, Mengqing Wang, Yinhe Luo, Jing Xie, L Jiao, Wei Tang, Yijue Deng, Bing Yao   +7 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

From kratom to 7-hydroxymitragynine: evolution of a natural remedy into a public-health threat. [PDF]

Pharm Biol
Alsbrook S, Pro G, Koturbash I.
europepmc   +1 more source

Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo

, 2014
Rebecca S. Rudicell, Young Do Kwon, Sung‐Youl Ko, Amarendra Pegu, Mark K. Louder, Ivelin S. Georgiev, Xueling Wu, Jiang Zhu, Jeffrey C. Boyington, Xuejun Chen, Wei Shi, Zhiyong Yang, Nicole A. Doria‐Rose, Krisha McKee, Sijy O’Dell, Stephen D. Schmidt, Gwo‐Yu Chuang, Aliaksandr Druz, Cinque Soto, Yongping Yang, Baoshan Zhang, Tongqing Zhou, John-Paul Todd, Krissey E. Lloyd, Joshua Eudailey, Kyle E. Roberts, Bruce R. Donald, Robert T. Bailer, Julie E. Ledgerwood, James C. Mullikin, Lawrence Shapiro, Richard A. Koup, Barney S. Graham, Martha Nason, Mark Connors, Barton F. Haynes, Srinivas S. Rao, Mario Roederer, Peter D. Kwong, John R. Mascola, Gary J. Nabel   +40 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Chemical proteomics decrypts the kinases that shape the dynamic human phosphoproteome

Bayer FP, Müller J, Kabella N, Abele M, Chang Y, Estrada Duenas LD, Jensen C, Hamood F, Lee C, Schneider A, The M, Kuster B.   +11 more
europepmc   +1 more source

The Effects of Quality of Reinforcement on the Resurgence of Responding. [PDF]

Behav Sci (Basel)
Romani PW.
europepmc   +1 more source