Results 21 to 30 of about 1,009,444 (403)

Development and Qualification of an Antigen Integrity Assay for a Plasmodium falciparum Malaria Transmission Blocking Vaccine Candidate, Pfs230

Vaccines, 2022
During development of a subunit vaccine, monitoring integrity of the recombinant protein for process development and quality control is critical. Pfs230 is a leading malaria transmission blocking vaccine candidate and the first to reach a Phase 2 ...
Kazutoyo Miura, Thao P. Pham, Shwu-Maan Lee, Jordan Plieskatt, Ababacar Diouf, Issaka Sagara, Camila H. Coelho, Patrick E. Duffy, Yimin Wu, Carole A. Long   +9 more
doaj   +1 more source

Afterthoughts | Complexities of Potency [PDF]

, 2019
Afterthoughts to themed perspectives on Complexities of ...
Lo, Vivienne
core   +3 more sources

Modifications at the C-Terminus To Improve Pyrrole−Imidazole Polyamide Activity in Cell Culture [PDF]

, 2009
Pyrrole−imidazole (Py-Im) hairpin polyamides are a class of small molecule DNA minor groove binding compounds that have been shown to modulate endogenous gene expression in cell culture.
Dervan, Peter B., Jacobs, Claire S.
core   +2 more sources

Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Frontiers in Pharmacology, 2021
Effective, safe, and pharmacokinetically suitable drugs are urgently needed to curb the ongoing COVID-19 pandemic. The main protease or 3C-like protease (Mpro or 3CLpro) of SARS-CoV-2 is considered an important target to formulate potent drugs ...
Hylemariam Mihiretie Mengist, Hylemariam Mihiretie Mengist, Hylemariam Mihiretie Mengist, Daniel Mekonnen, Daniel Mekonnen, Ahmed Mohammed, Ronghua Shi, Tengchuan Jin, Tengchuan Jin, Tengchuan Jin   +9 more
doaj   +1 more source

Introduction | Approaching Potent Substances in Medicine and Ritual across Asia [PDF]

, 2019
Introduction to themed research articles on Approaching Potent Substances in Medicine and Ritual across ...
Gerke, Barbara, van der Valk, Jan M. A.
core   +3 more sources

Ichthyofauna of Merbau River, Leuser Ecosystem Area, Indonesia: species composition, diversity, biometric condition, potency, and conservation status

The European Zoological Journal, 2023
The Leuser Ecosystem Area (LEA) is one of the largest conservation areas in Southeast Asia. However, the explorations of ichthyofauna at LEA are still relatively scarce compared to other vertebrates fauna.
M. Hidayat, S. Maulizar, A. S. Batubara, N. Kautsari, H. Latuconsina, F. M. Nur, I. Zulfahmi   +6 more
doaj   +1 more source

Mind the gap: Can we explain declining male reproductive health with known antiandrogens? [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Several countries have experienced rises in cryptorchidisms, hypospadias and testicular germ cell cancer. The reasons for these trends are largely unknown, but Skakkebaek
Andreas Kortenkamp, Berkowitz, Birkh  j, Carbone, Carmichael, Chia, Christiansen, Christiansen, Conacher, Covaci, Darbre, Ermler, Ermler, Fromme, Galassi, Hardell, Hardell, Hardell, Janjua, Jensen, Karrman, Karrman, Kjaerstad, Kojima, Kristensen, L  pez-Cervantes, Martin Scholze, Midasch, Neal, Nelson, Orton, Orton, Park, Pierik, Pierik, Rappaport, Schiavone, Schlumpf, Scholze, Sch  nfelder, Sibylle Ermler, Stoker, Suzuki, Swan, Swan, Vandenberg, Vinggaard, Wilson, Wine, You   +49 more
core   +1 more source

Pooled human bone marrow-derived mesenchymal stromal cells with defined trophic factors cargo promote dermal wound healing in diabetic rats by improved vascularization and dynamic recruitment of M2-like macrophages

Frontiers in Immunology, 2022
Human Mesenchymal Stromal Cells (hMSCs) are a promising source for cell-based therapies. Yet, transition to phase III and IV clinical trials is remarkably slow.
Hélène Willer, Hélène Willer, Gabriele Spohn, Kimberly Morgenroth, Corinna Thielemann, Susanne Elvers-Hornung, Peter Bugert, Bruno Delorme, Melanie Giesen, Thomas Schmitz-Rixen, Erhard Seifried, Christiane Pfarrer, Richard Schäfer, Richard Schäfer, Richard Schäfer, Karen Bieback, Karen Bieback, Karen Bieback   +17 more
doaj   +1 more source

A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias [PDF]

, 2017
Free Fatty Acid Receptor 2 is a GPCR activated by short chain fatty acids produced in high levels in the lower gut by microbial fermentation of non-digestible carbohydrates.
Aoki, Junken, Bolognini, Daniele, Hansen, Anders Højgaard, Hudson, Brian D., Inoue, Asuka, Kawakami, Kouki, Kishi, Takayuki, Milligan, Graeme, Sergeev, Eugenia, Ulven, Trond   +9 more
core   +3 more sources

The Buddhist–Medical Interface in Tibet: Black Pill Traditions in Transformation

Religions, 2019
This paper introduces Tibetan pill traditions and examines two exceptional pill formulas that emerged from an early Buddhist–medical interface in Tibet, but followed different trajectories due to the increased specialization of religious and ...
Barbara Gerke
doaj   +1 more source