Results 181 to 190 of about 469,402 (307)

Behavioural Effects and Naloxone Effectiveness With New Synthetic Opioids. [PDF]

Drug Alcohol Rev
Nielsen S, Silva JP, Jones JD, Krotulski A, Poovendran D, Muzangizi D, Forte G, White J, Comer SD.   +8 more
europepmc   +1 more source

Potency of Performance Test Using Microscopes

Journal of Research in Science Education, 2006
Mitsuhiro MIMASE, Kouichi MORIMOTO
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Exploratory evidence of mitigated immune imprinting following concomitant COVID-19 and influenza vaccination. [PDF]

NPJ Vaccines
Choi MJ, Gwak W, Yun JY, Ju HJ, Choi E, Cheong HJ, Kim WJ, Kim C, Kim HJ, Jang AY, Yoon S, Lee JW, Jeong HS, Song JY.   +13 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Ensuring vaccine cold chain integrity: A rapid and low-cost test for identifying heat-exposed sucrose-containing vaccines. [PDF]

Int J Pharm X
Arman BY, Magri A, Barbaglia MN, Petherbridge L, Brook J, Bharucha T, Legge I, Walsby-Tickle J, Deats M, Banerjee S, Mosca S, Jena R, Ranade DS, Chunekar SR, Patil KD, Gairola S, Merchant HA, Stokes R, Kuwana R, Maes A, James T, Green C, McCullagh J, Matousek P, Caillet C, Newton PN, Zitzmann N, Gangadharan B.   +27 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Potency of Performance Test Using Microscopes

Potency of Performance Test Using Microscopes
This purpose of this study is to show how to carry out a performance test with microscopes used in lower secondary schools and to examine their effectiveness. As a result of this study, we discovered the following: (1)It is possible to carry out a performance test of a microscope using a video camera; and, by doing so, the teacher can more properly ...
openaire  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Can therapeutic potency of a cancer nanomedicine be predicted by pain-related behavioral test in subcutaneous tumor model? [PDF]

Int J Pharm X
Tao Y, Cai X, Chen Z.
europepmc   +1 more source