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Potency Tests of Combination Vaccines [PDF]
Combination vaccines differ from single-component vaccines in composition and in how they are manufactured, which poses significant challenges to implementing effective quality-control tests, including measurement of potency. Because each combination vaccine is unique, existing guidelines often fail to provide sufficient information to overcome the ...
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In Algeria, vaccination against pertussis is carried out using the whole-cell pertussis vaccine combined with the diphtheria and tetanus toxoids (DTwp). The quality control of vaccines locally produced or imported is carried out before the batch release.
Khedidja Tahar djebbar +7 more
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Skin Sensitization Testing in Potency and Risk Assessment [PDF]
The purpose of this article is to review, and make recommendations for, the use of relevant skin sensitization test methods, for the purposes of determination of relative potency and the threshold dose necessary for the induction of skin sensitization, and for risk assessment.
Kimber, I. +11 more
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IntroductionAntibiotics are commonly used for the treatment and prevention of bacterial infections. The potency of antibiotics can be affected by factors such as temperature, light, moisture, and storage conditions.
Demelash Demissie +3 more
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Yield Performance of Locally Selected Cocoa Clones in North Luwu [PDF]
Participatory selection in North Luwu District selected some locally cocoa clones, of which MCC 01 and MCC 02 the most promising to be developed as clonal material.
Imran, I. (Imran) +2 more
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A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias [PDF]
Free Fatty Acid Receptor 2 is a GPCR activated by short chain fatty acids produced in high levels in the lower gut by microbial fermentation of non-digestible carbohydrates.
Aoki, Junken +9 more
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Diabetes is a medical condition in which the body cannot produce enough insulin to process the glucose in the blood. Type 2 diabetes is mostly diagnosed in order adults but it is increasingly seen in children, adolescent and younger adult.
Charity Ebelechukwu Okorie +1 more
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Coexpression of rat P2X2 and P2X6 subunits in Xenopus oocytes. [PDF]
Transcripts for P2X(2) and P2X(6) subunits are present in rat CNS and frequently colocalize in the same brainstem nuclei. When rat P2X(2) (rP2X(2)) and rat P2X(6) (rP2X(6)) receptors were expressed individually in Xenopus oocytes and studied under ...
Burnstock, G +5 more
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Microtitration of Rubella Virus in Monovalent Vaccinal Products [PDF]
Background: Potency test for control of rubella vaccine is a significant factor to qualify production line and vaccination program. For this reason, WHO recommends to use the microtitration method by both vaccine companies and control laboratories ...
F Esna-Ashari +9 more
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In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
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