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In Algeria, vaccination against pertussis is carried out using the whole-cell pertussis vaccine combined with the diphtheria and tetanus toxoids (DTwp). The quality control of vaccines locally produced or imported is carried out before the batch release.
Khedidja Tahar djebbar +7 more
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Skin Sensitization Testing in Potency and Risk Assessment [PDF]
The purpose of this article is to review, and make recommendations for, the use of relevant skin sensitization test methods, for the purposes of determination of relative potency and the threshold dose necessary for the induction of skin sensitization, and for risk assessment.
Kimber, I. +11 more
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IntroductionAntibiotics are commonly used for the treatment and prevention of bacterial infections. The potency of antibiotics can be affected by factors such as temperature, light, moisture, and storage conditions.
Demelash Demissie +3 more
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Diabetes is a medical condition in which the body cannot produce enough insulin to process the glucose in the blood. Type 2 diabetes is mostly diagnosed in order adults but it is increasingly seen in children, adolescent and younger adult.
Charity Ebelechukwu Okorie +1 more
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Microtitration of Rubella Virus in Monovalent Vaccinal Products [PDF]
Background: Potency test for control of rubella vaccine is a significant factor to qualify production line and vaccination program. For this reason, WHO recommends to use the microtitration method by both vaccine companies and control laboratories ...
F Esna-Ashari +9 more
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Comparative Assessment of the Whole-cell Pertussis Vaccine Potency Using Serological and Intracerebral Mouse Protection Methods [PDF]
One of the most important QC tests of whole-cell pertussis vaccine (WCPV) is potency test. In this regard, mouse protection test (MPT) is the current potency method, which is associated with severe animal distress and large variability in results.
D. Mohammadbagher, M. Noofeli, G. Karimi
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Prediction of the potency of bioactive compounds generally relies on linear or nonlinear quantitative structure–activity relationship (QSAR) models. Nonlinear models are generated using machine learning methods.
Tiago Janela +2 more
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Indian legal system makes it mandatory to medically examine any accused of rape as well as other forms of sexual assault. Accused is brought in the police custody for conducting medical examination which includes general physical examination, potency ...
Md Shadab Raheel +4 more
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Dengue fever has remained a continuing global medical threat that impacts half of the world’s population. Developing a highly effective dengue vaccine, with live-attenuated tetravalent vaccines as leading candidates, remains essential in preventing this ...
Yi Wang +9 more
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Rationalizing general limitations in assessing and comparing methods for compound potency prediction
Compound potency predictions play a major role in computational drug discovery. Predictive methods are typically evaluated and compared in benchmark calculations that are widely applied.
Tiago Janela, Jürgen Bajorath
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