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An Adenovirus Vaccine Potency Test

The Journal of Immunology, 1961
Summary Adenovirus vaccine potency estimates, based upon immune responses following multiple injections of fluid vaccine, were unreliable. As an alternative, a potency test based upon a single injection of vaccine with oil-adjuvant is described.
H, TINT, J, STONE
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Potency testing of acellular pertussis vaccines

Vaccine, 1992
The laboratory assessment of the potential of acellular pertussis vaccines to protect against human disease is a major problem. The mouse intracerebral challenge test, which is the accepted potency assay for whole cell pertussis vaccines, is not suitable for testing acellular vaccines, and more recently developed murine respiratory infection assays ...
A, Robinson, S G, Funnell
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Potency Testing of Live Measles Vaccine

Archives of Pediatrics & Adolescent Medicine, 1962
The preceding series of papers has furnished information pertaining to the number of infectious units of attenuated measles virus needed to immunize susceptible children. These presentations have also touched on the question of the optimum virus content of the live vaccine, both as it leaves the hands of the manufacturer and at the actual moment of ...
H M, MEYER   +3 more
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Potency Testing Clostridium chauvoei-Containing Bacterins: Relationship of Agglutination Titers and Potency Tests in Cattle

American Journal of Veterinary Research, 1972
SUMMARY A relationship was shown to exist between agglutination titers and immunologic responses of cattle vaccinated with experimentally produced and commercially available Clostridium chauvoei-containing bacterins. The immunity of vaccinated and control cattle was challenged with C. chauvoei spore F.
M E, Macheak, K D, Claus, S E, Maloy
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Comparisons of outlier tests for potency bioassays

Pharmaceutical Statistics, 2019
SummaryPotency bioassays are used to measure biological activity. Consequently, potency is considered a critical quality attribute in manufacturing. Relative potency is measured by comparing the concentration‐response curves of a manufactured test batch with that of a reference standard. If the curve shapes are deemed similar, the test batch is said to
Perceval Sondag   +4 more
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Simple potency test for LH-RH preparations

Journal of Biological Standardization, 1980
Proestrous rats, pretreated with fluphenazine dihydrochloride (FD) to block ovulation, were used to compare the ovulation-inducing activity of two synthetic LH-RH preparations; one was received from the National Institute for Biological Standards and Control labelled Gonadorelin acetate (77/596) and the other one was prepared in Ayerst Research ...
U K, Banik, M L, Givner
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Proposed Potency Testing of Smallpox Vaccine

The Journal of Immunology, 1961
Summary and Conclusions From the results of the studies described here, it is obvious that immediate application of titration in rabbit kidney tissue culture is a valid measure of smallpox vaccine potency only for the virus strain and passage levels employed.
V J Cabasso, I F Moore, M R Stebbins
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