Results 261 to 270 of about 468,048 (310)
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Potency Testing Clostridium chauvoei-Containing Bacterins: Relationship of Agglutination Titers and Potency Tests in Cattle

American Journal of Veterinary Research, 1972
SUMMARY A relationship was shown to exist between agglutination titers and immunologic responses of cattle vaccinated with experimentally produced and commercially available Clostridium chauvoei-containing bacterins. The immunity of vaccinated and control cattle was challenged with C. chauvoei spore F.
M E, Macheak, K D, Claus, S E, Maloy
openaire   +2 more sources

A comparison of methods for the potency test of rubella vaccine

Journal of Biological Standardization, 1977
Forty titrations of HPV/77 rubella vaccine by the cytopathic effect microassay and 26 titrations by the tube interference test were performed. The variance analysis of the results demonstrated that the cytopathic effect microassay is a more reliable method for the potency test of rubella vaccine.
M, Rapicetta, R, Santoro, M E, Grandolfo
openaire   +2 more sources

A review of the effectiveness of vaccine potency control testing

International Journal for Parasitology, 2003
The use of potency control testing is a valuable tool for testing the actual relative strength of manufactured assembly lots of vaccine. Biological-based manufacturing methods are inherently variable and potency testing is a tool to ensure lot-to-lot consistency of commercial vaccines.
David Scott, McVey   +2 more
openaire   +2 more sources

A One-Dose Potency Test for Poliomyelitis Vaccine

The Journal of Immunology, 1965
Summary Studies leading to the development and use of a one-dose potency test for poliomyelitis vaccine are described. The test is based on the measurement of neutralizing antibody in the serum of 6-week-old chickens that received one dose of a single dilution of vaccine.
R M, VANFRANK   +5 more
openaire   +2 more sources

A Guinea Pig Potency Test for Adenovirus Vaccine

The Journal of Immunology, 1960
Summary An assay for potency of adenovirus vaccine in guinea pigs based on the antigen extinction principle is described. The potency test values in repeat titrations were reproducible within a maximal 7-fold range. Further need for control with a standard reference vaccine is indicated. Potency values for a number of vaccines of diverse
L N, BINN, M R, HILLEMAN
openaire   +2 more sources

A potency test for live Newcastle disease vaccines

Journal of Biological Standardization, 1980
The potency of live Newcastle disease vaccines was assessed by means of a multi-point challenge assay in vaccinated chicks. The assay was shown to give reproducible results and to be capable of detecting significant differences between the protective capacities of various vaccines.
D H, Thornton, C N, Hebert
openaire   +2 more sources

Relative mutagenic potencies determined in the micronucleus test

Journal of Theoretical Biology, 1978
Abstract Data from two publications which include dose-response data were subject to model fitting using a Poisson distribution and a linear dose-response function. In Swiss mice, acetylaminofluorene was the weakest mutagen tested. Aflatoxin B 1 , 3-methylcholanthrene and dimethylnitrosamine were 66, 14, and 140 times as potent, respectively.
M A, Friedman   +3 more
openaire   +2 more sources

Simple potency test for LH-RH preparations

Journal of Biological Standardization, 1980
Proestrous rats, pretreated with fluphenazine dihydrochloride (FD) to block ovulation, were used to compare the ovulation-inducing activity of two synthetic LH-RH preparations; one was received from the National Institute for Biological Standards and Control labelled Gonadorelin acetate (77/596) and the other one was prepared in Ayerst Research ...
U K, Banik, M L, Givner
openaire   +2 more sources

A collaborative study on the potency testing of antirabies globulin

Journal of Biological Standardization, 1975
Studies have shown that Rabies Immune Globulin, Human, used in combination with vaccine, is most effective when given within a relatively narrow dose range. A dosage of 20 International Units (i.u.) per kg gave satisfactory results while 10 i.u./kg appeared to be insufficient for early protection and 40 i.u./kg may have interfered with optimal antibody
E A, Fitzgerald   +3 more
openaire   +2 more sources

A Simple Potency Test for Foot-and-Mouth Disease Vaccines in Mice and Comparison of Results with those of Potency Tests in Cattle

Zentralblatt für Veterinärmedizin Reihe B, 2010
Summary Adult mice vaccinated with monovalent foot-and-mouth disease vaccines prepared according to the Frenkel method developed complement fixing antibodies demonstrable by a modified direct complement-fixation test, which was called “complement-consumption test” (CCT) in distinction from conventional CFT.
E, Traub, P, Thein, F, Kesting
openaire   +2 more sources

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