Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Peer assessment assisted by technology
A common theme from the National Student Survey is that students want more feedback, but increasing the amount of teacher-student feedback is not practicable. Peer assessment, if carefully supported, can be a cost-effective solution.
Barr, Niall +7 more
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Integrating GIS and remote sensing for land use/land cover mapping and groundwater potential assessment for climate-smart cocoa irrigation in Ghana. [PDF]
Akpoti K +5 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A history of three e-assessment programmes in England
This article considers the use of e-assessment in England in three major education policy initiatives: the key stage 3 Information & Communication Technology (ICT) test, Basic & Key Skills (BKS) testing, and Functional Skills.
Sowerbutts, Paul +3 more
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AMAP Assessment 2015: Black Carbon and Ozone as Arctic Climate Forcers [PDF]
This assessment report presents the results of the 2015 AMAP Assessment of Black Carbon and Ozone as Arctic climate forcers.
Arctic Monitoring and Assessment Programme
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This report provides an environmental assessment of the proposed plans to install trunk sewer lines in and channelize the Singac and Naachtpunkt Brooks in Wayne Township.
core +1 more source
Whole-Genome Sequencing and Biotechnological Potential Assessment of Two Bacterial Strains Isolated from Poultry Farms in Belgorod, Russia. [PDF]
Senchenkov VY +12 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Is Rogō a viable alternative to Questionmark Perception in the Medical Sciences Division at Oxford?
The Medical Sciences Division (MSD) at the University of Oxford has a strong background in online assessment with Questionmark Perception. However, for the MSD, Perception does not fully deliver all of the potential benefits of e-assessment.
Mason, Jon, Young, Damion
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