Results 131 to 140 of about 15,304,650 (294)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Wellbeing assessment resource

open access: yes, 2017
The recently released Wellbeing Practice Guide, developed by the Victorian Department of Education (DET) and the Victorian Curriculum and Assessment Authority (VCAA) is designed to inform a greater understanding of wellbeing and its place as both a ...
Victorian Curriculum and Assessment Authority
core  

Forests community attitudes survey, Australia, 1990

open access: yes, 2019
This study was conducted as part of the Resource and Assessment Commission Forest and Timber Inquiry. It was designed to assess public opinion towards the environment, forests, and forest management in Australia.
Resource Assessment Commission
core   +1 more source

Towards a global One Health index: a potential assessment tool for One Health performance. [PDF]

open access: yesInfect Dis Poverty, 2022
Zhang XX   +37 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Assessment item generation, the way forward

open access: yes, 2014
Automatic item generation (AIG) supports in particular computerised adaptive testing, although it is now used in other contexts, in particular to extract items from learning texts or domain models.
Foulonneau, Muriel, Ras, Eric
core  

High Throughput Screening for Bioactive Components of Berberis baluchistanica Ahrendt Root and Their Functional Potential Assessment. [PDF]

open access: yesBiomed Res Int, 2022
Gul Z   +11 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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