Results 131 to 140 of about 20,735,341 (389)

The Navier-Stokes equations for Incompressible Flows: solution properties at potential blow-up times [PDF]

, 2015
Jens Lorenz, Paulo R. Zingano
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Unveiling the Potential of Novel Macrophytes for the Treatment of Tannery Effluent in Vertical Flow Pilot Constructed Wetlands [PDF]

, 2020
Sobia Ashraf, Muhammad Naveed, Muhammad Afzal, Mahmoud F. Seleiman, Nasser Al-Suhaibani, Zahir A. Zahir, Adnan Mustafa, Yahya Refay, Bushra Ahmed Alhammad, Sana Ashraf, Majed A. Alotaibi, Kamel A. Abdella   +11 more
openalex   +1 more source

A geometry package for generation of input data for a three-dimensional potential-flow program [PDF]

The preparation of geometric data for input to three-dimensional potential flow programs was automated and simplified by a geometry package incorporated into the NASA Langley version of the 3-D lifting potential flow program.
Halsey, N. D., Hess, J. L.
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Interaction of 4-Hydroxylated Estradiol and Potential- Sensitive Ca2+ Channels in Altering Uterine Blood Flow during the Estrous Cycle and Early Pregnancy in Gilts1 [PDF]

, 1987
Steven L. Stice, Stephen P. Ford, John P. N. Rosazza, D. E. Van Orden   +3 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

South Korea’s potential export flow: a panel gravity approach [PDF]

, 2018
Kashif Imran
openalex   +1 more source

Residual Flow Inside the Woven EndoBridge Device at Follow-Up: Potential Predictors of the Bicêtre Occlusion Scale Score 1 Phenomenon [PDF]

, 2020
Marie Teresa Nawka, AW Lohse, Maxim Bester, Jens Fiehler, Jan‐Hendrik Buhk   +4 more
openalex   +1 more source