Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Laboratory Measurements of Zeta Potential in Fractured Lewisian Gneiss: Implications for the Characterization of Flow in Fractured Crystalline Bedrock [PDF]
, 2021 J. Vinogradov +4 more
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Fluid flow properties of the Wilhelmøya Subgroup, a potential unconventional CO2 storage unit in central Spitsbergen [PDF]
, 2018 Mark Joseph Mulrooney +9 more
openalex +1 more source
A new statistical method to assess potential debris flow erosion [PDF]
, 2023 G. Bertoldi +3 more
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Finite element analysis of low speed viscous and inviscid aerodynamic flows [PDF]
A weak interaction solution algorithm was established for aerodynamic flow about an isolated airfoil. Finite element numerical methodology was applied to solution of each of differential equations governing potential flow, and viscous and turbulent ...
Baker, A. J., Manhardt, P. D.
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
ADDED RESISTANCE IN WAVES OF INTACT AND DAMAGED SHIP IN THE ADRIATIC SEA
Brodogradnja, 2015 In this paper the ship added resistance in regular head waves and at different sea states in a certain frequency range at different forward speeds was calculated. Calculations were conducted using hydrodynamic software.
Ivana Martić +2 more
doaj
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Repetitive and Brief Occlusion of the Majority of the Vena Cava Flow Attenuates Pulmonary Arterial Hypertension and Improves I K+ of the Pulmonary Arterial Smooth Muscle Cells in Rat Models: a novel potential therapeutic strategy for PAH [PDF]
, 2020 Nan Liu, Ying Xing, Wang Lv, Chen Wang
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