Results 131 to 140 of about 2,577,081 (317)
Potential flow through a cascade of aerofoils: direct and inverse problems. [PDF]
Proc Math Phys Eng Sci, 2018 Baddoo PJ, Ayton LJ.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
, 2016 Earlier studies suggest that individual differences in flow experiences depend on both situational variables, e.g. the environmental opportunities to engage in flow promoting activities, and personal traits.
Guy Madison +11 more
core +1 more source
Tracing the Potential Flow of Consumer Data: A Network Analysis of Prominent Health and Fitness Apps. [PDF]
J Med Internet Res, 2017 Grundy Q, Held FP, Bero LA.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Water flow through tailings dams [PDF]
, 1993 Water levels in tailings dams are generally lower than those of standard earth dams. Previously, other authors have shown that embankment geometry and variation in permeability can be responsible for a concave upwards steady state seepage line.
Welch, Jonathan Paul
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The impact of heart rate and cardiac output on the flow in the human thoracic aorta
Purpose: The purpose of the study is to determine the effects of heart rate (HR) and cardiac output(CO), in the temporal variation of CO on flow structures and related biomechanical markers. Methods: The pulsatile flow in the thoracic aorta was simulated
Prahl Wittberg, Lisa +2 more
core +1 more source