Results 71 to 80 of about 2,577,081 (317)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Enhanced Drag in Pipe Turbulent Flow by an Aqueous Electrolyte: an Electroviscous Effect [PDF]

open access: yes, 2009
Drag enhancement is reported for turbulent pipe flow of aqueous electrolyte solutions. No electroviscous effect was obtained with laminar flow. Nor was any unusual pressure drop observed for laminar or turbulent flow of non-electrolyte aqueous solutions ...
Chen, John J. J.   +8 more
core   +1 more source

Paradox of description for motion of a hydrodynamic discontinuity in a potential and incompressible flow

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2023
Hydrodynamic discontinuities in an external potential and incompressible flow are investigated. Using the reaction front as an example in a 2D stream, an overdetermined system of equations is obtained that describes its motion in terms of the surface ...
Maksim L. Zaytsev   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

pflow.py a Potential Flow Solver and Visualizer

open access: yes, 2018
plow.py is a simple teaching and analysis tool for 2-D Potential Flows. It is a collection of code, that allows the construction of simple flow fields that meet the Potential Flow governing Equations.
Jahn, Ingo
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Gas bubbles have controversial effects on Taylor flow electrochemistry

open access: yes, 2021
Electrochemistry is currently resurging in popularity amongst synthetic chemists due to the unique opportunities it provides to activate organic molecules. Simultaneously, continuous-flow technology has been used to enable scalability and to increase the
Soares, Cíntia   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A New Method of Measuring Velocity Profiles using a MultiElectrode Electromagnetic Flow Meter

open access: yes, 2010
This paper describes a model of a novel design of electromagnetic flow meter for velocity profile measurement in single phase and multiphase flows with nonuniform axial velocity profiles.
Lucas, Gary, Leeungculsatien, Teerachai
core  

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