Results 91 to 100 of about 13,662,793 (258)
Integrated Synthetic Platforms for Chemical Probes: A Journey through the Routes of Flow Processing
, 2017 The talk will focus on our recent efforts directed towards the design and implementation of integrated flow platforms for the production of chemical probes and compound library in drug discovery ...
Gioiello, A.
core
Optimization of wind farm layout [PDF]
FME Transactions, 2010 This paper presents a method for determination of optimum positions of single wind turbines within the wind farms installed on arbitrary configured terrains, in order to achieve their maximum production effectiveness.
Rašuo Boško P., Bengin Aleksandar Č.
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Multiparametric flow cytometry and cell sorting for the assessment of viable, injured, and dead bifidobacterium cells during bile salt stress [PDF]
, 2002 Using a flow cytometry-based approach, we assessed the viability of Bifidobacterium lactis DSM 10140 and Bifidobacterium adolescentis DSM 20083 during exposure to bile salt stress.
Breeuwer, P. +7 more
core
Multiple solutions and stability of the steady transonic small-disturbance equation
Theoretical and Applied Mechanics Letters, 2017 Numerical solutions of the steady transonic small-disturbance (TSD) potential equation are computed using the conservative Murman−Cole scheme. Multiple solutions are discovered and mapped out for the Mach number range at zero angle of attack and the ...
Ya Liu, Shijun Luo, Feng Liu
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Reduced-order aerodynamic model of a starting plate with discrete-vortex merging
Frontiers in PhysicsThis study employs potential flow theory with a discrete-vortex method to model the unsteady aerodynamics of a flat plate, with a particular focus on the coupled dynamics of leading-edge and trailing-edge vortices (LEVs and TEVs).
Xi Xia, Lingyun Shangguan
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
ADDED RESISTANCE IN WAVES OF INTACT AND DAMAGED SHIP IN THE ADRIATIC SEA
Brodogradnja, 2015 In this paper the ship added resistance in regular head waves and at different sea states in a certain frequency range at different forward speeds was calculated. Calculations were conducted using hydrodynamic software.
Ivana Martić +2 more
doaj