Results 101 to 110 of about 2,577,081 (317)
Nonlinear ship wave simulation using an automatic mesh generation method
Objectives To simulate the complex nonlinear interactions between the free surface and instantaneous wetted hull surface during ship navigation, an automatic mesh generation method is proposed.MethodsThe method takes a whole-hull triangular mesh file as ...
Kaiyuan SHI +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A simple analytical expression is derived to describe the connection between the pressure coefficient distribution over the surface of a 2D airfoil and the angle of attack for steady incompressible potential flow.
A. Segalini, TALAMELLI, ALESSANDRO
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
In this investigation, we introduce a new meromorphic operator defined by meromorphic univalent functions. A new class of meromorphic functions is introduced by this operator, which can generate several distinct subclasses depending on the values of its ...
Aya F. Elkhatib +3 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
An Analytical Method for Reconstruction of Velocity Profiles using a Multi-Electrode Electromagnetic Flow Meter [PDF]
An analytical method is developed for the reconstruction of velocity profiles using measured potential distributions obtained around the boundary of a multi-electrode electromagnetic flow meter.
Zhang, Zhichao +2 more
core +1 more source
Wake flow past a submerged plate near a free surface
A wake model is pursued for potential flow past a submerged, finite-length plate that is perpendicular to a uniform, horizontal stream bounded above by a free surface. The effects of gravity are included along the free surface.
E. McLean +2 more
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Active control of hydrodynamic slug flow [PDF]
Multiphase flow is associated with concurrent flow of more than one phase (gas-liquid, liquid-solid, or gas-liquid-solid) in a conduit. The simultaneous flow of these phases in a flow line, may initiate a slug flow in the pipeline. Hydrodynamic slug flow
Inyiama, Fidelis Chidozie
core

