Results 81 to 90 of about 13,662,793 (258)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The fundamentals behind the use of flow reactors in electrochemistry [PDF]

open access: yes, 2019
ConspectusIn the past decade, research into continuous-flow chemistry has gained a lot of traction among researchers in both academia and industry.
Yiran Cao   +9 more
core   +2 more sources

Pressure and Velocity Profiles over a Weir Using Potential Flow Model

open access: yesFluids
A potential flow model of the semi-inverse type is proposed to simulate flow over round crested weirs. This technique involves the construction of only streamlines over the weir instead of constructing the entire flow net.
M. R. Ajith Kumar   +2 more
doaj   +1 more source

Flow in Fractured Porous Media Modeled in Closed-Form: Augmentation of Prior Solution and Side-Stepping Inconvenient Branch Cut Locations

open access: yesFluids, 2020
Carefully chosen complex variable formulations can solve flow in fractured porous media. Such a calculus approach is attractive, because the gridless method allows for fast, high-resolution model results.
Ruud Weijermars, Aadi Khanal
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Observed long-term changes in UK river flow patterns: a review [PDF]

open access: yes, 2013
The aim of this paper is to provide a state-of-the-art assessment of the evidence for long-term river flow changes in the UK. This paper necessarily focuses on climate-driven changes in flow, as opposed to capturing changes caused by human influences ...
Hannaford, Jamie
core   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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