Results 81 to 90 of about 20,735,341 (389)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Two‐Dimensional Free Surface Flow Through Solid Walls With Surface Tension Effects

Engineering Reports
We examine the two‐dimensional, steady, and irrotational flow of an inviscid and incompressible fluid emerging from certain cases of flow through solid walls. Surface tension (T) is considered, while gravitational effects are neglected.
Zineb Guellati, Abdelkader Gasmi
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Paradox of description for motion of a hydrodynamic discontinuity in a potential and incompressible flow

Известия высших учебных заведений. Поволжский регион: Физико-математические науки, 2023
Hydrodynamic discontinuities in an external potential and incompressible flow are investigated. Using the reaction front as an example in a 2D stream, an overdetermined system of equations is obtained that describes its motion in terms of the surface ...
Maksim L. Zaytsev, Vyacheslav B. Akkerman   +1 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Potential for gene-flow from cultivated Irish grasses and cereals [PDF]

, 2009
End of project reportThe importance of gene movement from cultivated plants has been highlighted in regard to minimising the movement of seed and/or pollen between GM and non-GM crops (i.e. gene flow). Although ryegrass covers in excess of 90% of Ireland’
Meade, Connor, Mullins, Ewen, Ryan, Eimear   +2 more
core  

BPS dyons and Hesse flow

, 2012
We revisit BPS solutions to classical N=2 low energy effective gauge theories. It is shown that the BPS equations can be solved in full generality by the introduction of a Hesse potential, a symplectic analog of the holomorphic prepotential.
A Strominger, B Bates, B Craps, D Alekseevsky, Dieter Van den Bleeken, DS Freed, E Witten, EJ Weinberg, F Denef, F Denef, F Denef, G Cardoso, G Lopes Cardoso, G Lopes Cardoso, H Kim, H Ooguri, IA Popescu, J Boer de, J Manschot, JH Schwarz, JM Maldacena, K Behrndt, K-M Lee, LF Alday, MK Gaillard, N Seiberg, N Seiberg, NJ Hitchin, O Bergman, P Argyres, S Deser, S Ferrara, S Ferrara, S Ferrara, S Ferrara, S Lee, T Dimofte, T Mohaupt, V Cortes, W Sabra, W Sabra, Y Tachikawa   +41 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source