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Circulating Histones in Sepsis: Potential Outcome Predictors and Therapeutic Targets [PDF]

open access: yesFrontiers in Immunology, 2021
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection and is associated with high morbidity and mortality. Circulating histones (CHs), a group of damage-associated molecular pattern molecules mainly
Yupei Li   +16 more
doaj   +2 more sources

Discovery of genes positively modulating treatment effect using potential outcome framework and Bayesian update [PDF]

open access: yesBMC Medical Informatics and Decision Making, 2022
Background The recent explosion of cancer genomics provides extensive information about mutations and gene expression changes in cancer. However, most of the identified gene mutations are not clinically utilized. It remains uncertain whether the presence
Youngkeun Lee, Jisoo Kim, Sung Wook Seo
doaj   +2 more sources

With Potential Games, Which Outcome Is Better? [PDF]

open access: yesGames, 2020
Lower one- or two-dimensional coordination, or potential games, are popularly used to model interactive behavior, such as innovation diffusion and cultural evolution. Typically, this involves determining the “better” of competing solutions.
Santiago Guisasola, Donald Saari
doaj   +3 more sources

Medication Errors in Vietnamese Hospitals: Prevalence, Potential Outcome and Associated Factors. [PDF]

open access: yesPLoS ONE, 2015
Evidence from developed countries showed that medication errors are common and harmful. Little is known about medication errors in resource-restricted settings, including Vietnam.To determine the prevalence and potential clinical outcome of medication ...
Huong-Thao Nguyen   +4 more
doaj   +2 more sources

Intraocular pressure-lowering effects of Ripasudil: a potential outcome marker for Trabeculotomy [PDF]

open access: yesBMC Ophthalmology, 2019
Background To examine the use of ripasudil as a trabeculotomy outcome marker in patients with primary open-angle glaucoma (POAG). Methods Between May 2015 and December 2018, 35 eyes underwent trabeculotomy and were postoperatively followed for over 3 ...
Erina Goda   +3 more
doaj   +2 more sources

Using Multiple Imputation to Classify Potential Outcomes Subgroups [PDF]

open access: greenStatistical Methods in Medical Research, 2020
With medical tests becoming increasingly available, concerns about over-testing, over-treatment and health care cost dramatically increase. Hence, it is important to understand the influence of testing on treatment selection in general practice. Most statistical methods focus on average effects of testing on treatment decisions.
Yun Li   +4 more
openalex   +5 more sources

Identifiability and Estimation for Potential-Outcome Means with Misclassified Outcomes

open access: yesMathematics
Potential outcomes play a fundamental and important role in many causal inference problems. If the potential-outcome means are identifiable, a series of causal effect measures, including the risk difference, the risk ratio, and the treatment benefit rate,
Shaojie Wei   +3 more
doaj   +2 more sources

Potential outcome and decision theoretic foundations for statistical causality

open access: yesJournal of Causal Inference, 2023
In a recent work published in this journal, Philip Dawid has described a graphical causal model based on decision diagrams. This article describes how single-world intervention graphs (SWIGs) relate to these diagrams.
Richardson Thomas S., Robins James M.
doaj   +1 more source

Causation and decision: On Dawid’s “Decision theoretic foundation of statistical causality”

open access: yesJournal of Causal Inference, 2022
In a recent issue of this journal, Philip Dawid (2021) proposes a framework for causal inference that is based on statistical decision theory and that is, in many aspects, compatible with the familiar framework of causal graphs (e.g., Directed Acyclic ...
Pearl Judea
doaj   +1 more source

Definition and Estimation of Covariate Effect Types in the Context of Treatment Effectiveness

open access: yesMathematics, 2020
In some clinical studies, assessing covariate effect types indicating whether a covariate is predictive and/or prognostic is of interest, in addition to the study endpoint. Recently, for a case with a binary outcome, Chiba (Clinical Trials, 2019; 16: 237–
Yasutaka Chiba
doaj   +1 more source

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