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Circulating Histones in Sepsis: Potential Outcome Predictors and Therapeutic Targets [PDF]

open access: yesFrontiers in Immunology, 2021
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection and is associated with high morbidity and mortality. Circulating histones (CHs), a group of damage-associated molecular pattern molecules mainly
Yupei Li   +16 more
doaj   +2 more sources

Identifiability and Estimation for Potential-Outcome Means with Misclassified Outcomes

open access: yesMathematics
Potential outcomes play a fundamental and important role in many causal inference problems. If the potential-outcome means are identifiable, a series of causal effect measures, including the risk difference, the risk ratio, and the treatment benefit rate,
Shaojie Wei   +3 more
doaj   +3 more sources

Discovery of genes positively modulating treatment effect using potential outcome framework and Bayesian update [PDF]

open access: yesBMC Medical Informatics and Decision Making, 2022
Background The recent explosion of cancer genomics provides extensive information about mutations and gene expression changes in cancer. However, most of the identified gene mutations are not clinically utilized. It remains uncertain whether the presence
Youngkeun Lee, Jisoo Kim, Sung Wook Seo
doaj   +2 more sources

Medication Errors in Vietnamese Hospitals: Prevalence, Potential Outcome and Associated Factors. [PDF]

open access: yesPLoS ONE, 2015
Evidence from developed countries showed that medication errors are common and harmful. Little is known about medication errors in resource-restricted settings, including Vietnam.To determine the prevalence and potential clinical outcome of medication ...
Huong-Thao Nguyen   +4 more
doaj   +2 more sources

Intraocular pressure-lowering effects of Ripasudil: a potential outcome marker for Trabeculotomy [PDF]

open access: yesBMC Ophthalmology, 2019
Background To examine the use of ripasudil as a trabeculotomy outcome marker in patients with primary open-angle glaucoma (POAG). Methods Between May 2015 and December 2018, 35 eyes underwent trabeculotomy and were postoperatively followed for over 3 ...
Erina Goda   +3 more
doaj   +2 more sources

Potential risk factors for poor outcome after anterior surgery for patients with cervical ossification of the posterior longitudinal ligament

open access: yesTherapeutics and Clinical Risk Management, 2018
Shaoqing Li, Peng Zhang, Xianda Gao, Dechao Miao, Yanlong Gao, Yong Shen Department of Orthopedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China Objective: Our purpose here was to identify risk ...
Li SQ   +5 more
doaj   +1 more source

Noncoding RNAs as potential biomarkers to predict the outcome in pancreatic cancer

open access: yesDrug Design, Development and Therapy, 2015
Kaizhou Jin,1–3,* Guopei Luo,1–3,* Zhiwen Xiao,1–3 Zuqiang Liu,1–3 Chen Liu,1–3 Shunrong Ji,1–3 Jin Xu,1–3 Liang Liu,1–3 Jiang Long,1–3 Quanxing Ni,1–3 Xianjun Yu1–3 1Department of ...
Jin K   +10 more
doaj   +1 more source

Potential outcome and decision theoretic foundations for statistical causality

open access: yesJournal of Causal Inference, 2023
In a recent work published in this journal, Philip Dawid has described a graphical causal model based on decision diagrams. This article describes how single-world intervention graphs (SWIGs) relate to these diagrams.
Richardson Thomas S., Robins James M.
doaj   +1 more source

Causation and decision: On Dawid’s “Decision theoretic foundation of statistical causality”

open access: yesJournal of Causal Inference, 2022
In a recent issue of this journal, Philip Dawid (2021) proposes a framework for causal inference that is based on statistical decision theory and that is, in many aspects, compatible with the familiar framework of causal graphs (e.g., Directed Acyclic ...
Pearl Judea
doaj   +1 more source

Definition and Estimation of Covariate Effect Types in the Context of Treatment Effectiveness

open access: yesMathematics, 2020
In some clinical studies, assessing covariate effect types indicating whether a covariate is predictive and/or prognostic is of interest, in addition to the study endpoint. Recently, for a case with a binary outcome, Chiba (Clinical Trials, 2019; 16: 237–
Yasutaka Chiba
doaj   +1 more source

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