Results 241 to 250 of about 5,371,394 (318)

The Impact of Pre-Stem Cell Transplant Ferritin Level on Late Transplant Complications: An Analysis to Determine the Potential Role of Iron Overload on Late Transplant Outcomes

, 2010
Yvonne A. Efebera, Rupinderjit S Thandi, Rima M. Saliba, Uday Popat, Marcos de Lima, Amin M. Alousi, Chitra Hosing, Gabriela Rondón, Richard E. Champlin, Sergio Giralt   +9 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Lifestyle behaviors, serum metabolites and high myopia: Mendelian randomization and mediation analysis. [PDF]

Int J Ophthalmol
Liu NE, Xu XT, Yu XB.
europepmc   +1 more source

Long‐term mental health outcomes after corneal transplantation and potential predictors: A multicentre prospective cohort study [PDF]

Ellen B. M. Elsman, Hilde P. A. van der Aa, N. Billingy, Carla P. Nieuwendaal, Robert P. L. Wisse, Robert H.J. Wijdh, Mhy Tang, Bart T. H. van Dooren, Siamak Nobacht, Rudy M.M.A. Nuijts, Ger H. M. B. van Rens, Ruth M. A. van Nispen   +11 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Evaluating Methods for High-Dimensional Mediation in Metabolomics Data. [PDF]

Environ Sci Technol
Hoffman SS, Liang D, Dunlop A, Everson T, Gaskins AJ, Jones DP, Hüls A, Marcus M, Naimi AI.   +8 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Potential for Algorithmic Bias in Clinical Decision Instrument Development. [PDF]

NPJ Digit Med
Obra JK, Singh C, Watkins K, Feng J, Obermeyer Z, Kornblith A.   +5 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A framework for thinking about the potential public health impact of epidemiologic research. [PDF]

Epidemiology
Lesko CR, Zalla LC, Ross RK, Rudolph JE, Smith ER, Edwards JK.   +5 more
europepmc   +1 more source