Results 111 to 120 of about 100,942 (213)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Identification and Translocation of Potentially Toxic Elements in Sorghum Plants Grown in Central Mexico. [PDF]

Toxics
Herrera-Figueroa LE, Rodríguez-González F, Figueroa-Brito R, Herrera-Cadena SM, Vargas-Solano SV, Osorio-Ruiz A, Correa-Ramírez MM, Ail-Catzim CE, Gutiérrez-Yurrita PJ, Alcántara-Cárdenas JA.   +9 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Microbial community in alfalfa rhizosphere in response to rhizobial inoculation under increased concentrations of potentially toxic elements. [PDF]

Front Plant Sci
Pešić M, Sikirić B, Mrvić V, Buzurović U, Tošić Jojević S, Andjelković S, Stajković-Srbinović O.   +6 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Unraveling the Origins and Drivers of Potentially Toxic Elements (PTEs): A Sequential Framework Integrating Receptor Model and Machine Learning. [PDF]

Toxics
Wang J, Zhao X, Liu J, Yan Y, Zhao W, Xia C, Zheng J, Liu J.   +7 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Invasive Plants as Accumulators of Heavy Metals and Potentially Toxic Elements: A Review with Implications for Remediation. [PDF]

Plants (Basel)
Miletić Z, Mitrović M, Sekulić D, Jarić S, Radulović N, Jonjev M, Pavlović P.   +6 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Ornamental Phytoremediation in Cities: Context-Dependent Roles in Managing Potentially Toxic Elements. [PDF]

Plants (Basel)
Horotán K, Orlóci L, Táborská J, Mosonyi ID, Neményi A, Boronkay G, Istvánfi Z, Kisvarga S.   +7 more
europepmc   +1 more source