Results 111 to 120 of about 1,787,106 (304)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Jet Interactions with the Hot Halos of Clusters and Galaxies [PDF]

open access: yes, 2007
X-ray observations of cavities and shock fronts produced by jets streaming through hot halos have significantly advanced our understanding of the energetics and dynamics of extragalactic radio sources.
Birzan, L.   +5 more
core   +1 more source

Extended ASP tableaux and rule redundancy in normal logic programs

open access: yes, 2008
We introduce an extended tableau calculus for answer set programming (ASP). The proof system is based on the ASP tableaux defined in [Gebser&Schaub, ICLP 2006], with an added extension rule.
Anger   +17 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Design Of A Doherty Power Amplifier For GSM Systems

open access: yesTikrit Journal of Engineering Sciences, 2013
This paper presents the design and analysis of Doherty power amplifier. The Doherty amplifier is used in  a base station for mobile system because of its high efficiency.
Saad Wasmi Osman
doaj  

Are Radio AGN Powered by Accretion or Black Hole Spin?

open access: yes, 2010
We compare accretion and black hole spin as potential energy sources for outbursts from AGN in brightest cluster galaxies (BCGs). Based on our adopted spin model, we find that the distribution of AGN power estimated from X-ray cavities is consistent with
B. R. McNamara   +35 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

High power added efficiency at 35 GHz on InP DHHEMTs

open access: yesElectronics Letters, 1998
A /spl delta/ doped AlInAs/GaInAs on InP high electron mobility transistors (HEMTs) has been realised with an AlAs/AlInAs superlattice barrier layer and a gate length of 0.25 /spl mu/m. A very high breakdown voltage of 10 V when the device is operated as a transistor has been demonstrated.
C. Gaquiere   +3 more
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Amplificador de Potencia Clase-S para Transmisor EER [PDF]

open access: yes, 2008
A Class-S power amplifier for an EER transmitter is shown in this paper. Simulations and measurements on a circuit prototype are presented showing good agreement. The amplifier is based on MOSFET technology both for the power stage and driver.
Gimeno Martín, Alejandro   +3 more
core  

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