Results 241 to 250 of about 1,292,199 (328)

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

open access: yesAdvanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong   +22 more
wiley   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

open access: yesAdvanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu   +17 more
wiley   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu   +8 more
wiley   +1 more source

Active Thermal Metasurfaces Enable Superscattering of Thermal Signatures Across Arbitrary Shapes and Thermal Conductivities

open access: yesAdvanced Science, EarlyView.
This study proposes a thermal superscatterer capable of manipulating thermal scattering signatures far exceeding the actual scale of objects. Utilizing transformation thermotics and active thermal metasurfaces, the device reproduces the thermal scattering signature of the enlarged thermal scatterer.
Yichao Liu   +9 more
wiley   +1 more source

Robust DNNs for power allocation problems in cognitive relay networks

open access: green
Yacine Benatia   +3 more
openalex   +1 more source

Empowering Flexible Electronics with Piezoelectric Nanogenerators: Breakthroughs from Energy Harvesting to Intelligent Sensing

open access: yesAdvanced Science, EarlyView.
This review systematically summarizes recent advances in self‐powered flexible sensing and energy storage systems based on piezoelectric nanogenerators (PENGs). It highlights their fundamental mechanisms, structural designs, and applications in health monitoring, e‐skin, and tactile sensing. The integration of PENGs with supercapacitors or batteries is
Wu‐Lin Xin   +8 more
wiley   +1 more source

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