Results 71 to 80 of about 21,355 (312)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Wideband LTE power amplifier with integrated novel analog pre-distorter linearizer for mobile wireless communications.

PLoS ONE, 2014
For the first time, a new circuit to extend the linear operation bandwidth of a LTE (Long Term Evolution) power amplifier, while delivering a high efficiency is implemented in less than 1 mm2 chip area. The 950 µm × 900 µm monolithic microwave integrated
Eswaran Uthirajoo, Harikrishnan Ramiah, Jeevan Kanesan, Ahmed Wasif Reza   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Ultra Wideband High-Efficiency High-Power Amplifier Design by Simplified Output Matching Technique

This paper presents the design of a Gallium Nitride (GaN) transistor-based ultra-wideband (UWB) high-efficiency power amplifier (PA) with 25W (44 dBm) output power operating in the 2–6 GHz frequency band. The design of the matching circuits is based on a
Metin Yazgı, Engin Çağdaş, Oğuzhan Kızılbey   +2 more
core   +1 more source

Design of an E-band Doherty Power amplifier

, 2018
This paper demonstrates the design of an E-band Doherty power amplifier (PA) based in an 130nm SiGe BiCMOS process. This design includes main and auxiliary amplifiers, lange coupler and a pre-amplifier.
Parveg, Dristy, Halonen, Kari A.I., Najmussadat, Md, Varonen, Mikko; id_orcid, Ahamed, Raju   +4 more
core   +1 more source

Temperature-Characteristic Survey of a 1000-W LDMOS Power Amplifier

IEEE Access
To investigate the temperature characteristics of a laterally double-diffused metal oxide semiconductor (LDMOS) 1000 W shortwave solid-state power amplifier (PA), a comprehensive series of tests has been conducted.
Qian Lin, Da-An Zhao, Mei-Qian Wang, Fei You, Ji-Hua Wu, Ying-Chun Lv   +5 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

19~21 GHz GaAs high linearity power amplifier MMIC

Dianzi Jishu Yingyong
Based on a technology of 0.15 μm GaAs high electron mobility transistor (pHEMT), a 19~21 GHz high linearity power amplifier MMIC was demonstrated in this paper.
Liu Xiaoyu, Han Chenghao, Ruan Wenwu, Guo Runnan, Liu Ling, Xu Xindong, Hou Zewen, Zhuang Yuan, Yu Xuming, Tao Hongqi   +9 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

5.2 GHz variable-gain amplifier and power amplifier driver for WLAN IEEE 802.11a transmitter front-end

, 2009
A 5.2 GHz variable-gain amplifier (VGA) and a power amplifier (PA) driver are designed for WLAN IEEE 802.11a monolithic RFIC. The VGA and the PA driver are implemented in a 50 GHz 0.35 μm SiGe BiCMOS technology and occupy 1.12×1.25 mm~2 die area. The VGA
Zhang Xuelian, Shi Yin, Dai Fa Foster, Yan Jun   +3 more
core