Results 61 to 70 of about 670,349 (316)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Evaluation of Loss Coefficient For Stand Alone Radiator

open access: yes, 2010
In the UK, domestic heating contributes to about 40% of annual energy consumption. Effective and efficient heating systems are essential to drive the cost of heating down.
Barrans, Simon   +10 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Effect of Blade Pitch Angle on the Aerodynamic Characteristics of a Straight-bladed Vertical Axis Wind Turbine Based on Experiments and Simulations

open access: yesEnergies, 2018
The blade pitch angle has a significant influence on the aerodynamic characteristics of horizontal axis wind turbines. However, few research results have revealed its impact on the straight-bladed vertical axis wind turbine (Sb-VAWT). In this paper, wind
Yanzhao Yang   +4 more
doaj   +1 more source

Power series with almost periodic coefficients [PDF]

open access: yesProceedings of the American Mathematical Society, 1967
and that the corresponding limit at x = e(O), where 0 is not congruent (mod 1) to an integral multiple of a, is zero. P. Sziisz has pointed out that for the proof of (1) and (2) Davenport's conditions can be reduced to the following: (a) limN_. EInIN ane(nt) exist for each real t, and (b) I E jnI,N a.e(nt) I
openaire   +1 more source

Prime power divisors of binomial coefficients. [PDF]

open access: yesJournal für die reine und angewandte Mathematik (Crelles Journal), 1992
[No abstract available]
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A Mode-Switching Based Phase Shift Control for Optimized Efficiency and Wide ZVS Operations in Wireless Power Transfer Systems [PDF]

open access: yes, 2023
This article proposes a mode-switching-based phase shift control (MS-PSC) for wireless power transfer (WPT) systems, which is able to achieve power regulation, load matching, and wide ZVS operations simultaneously without using additional dc-dc ...
Soeiro, Thiago Batista   +6 more
core   +1 more source

Renewable Energy Technology: Transient 3D CFD and Experimental Electrical Evaluation of a Cycloidal-Enhanced Rotor Versus a Savonius and Gorlov-Savonius Rotor with Blade Rotation Angle

open access: yesTechnologies
This study presents a numerical and experimental analysis of vertical-axis Cycloidal rotors (RC) versus Savonius rotors (RS), with and without coupling to a Gorlov rotor (RG), designed to operate under low wind speed conditions of 2.5 m/s.
María Angélica Luján Vega   +5 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy