Results 31 to 40 of about 4,857,649 (284)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A step-down nesting-type ac–ac converter combined with voltage equalizers and switched-capacitor simple converters

open access: yesEnergy Reports, 2020
In this paper, we present an inductor-less direct ac–ac converter with improved nesting-type topology. Unlike existing direct ac–ac converters, the proposed ac–ac converter combines a voltage equalizer and a switched-capacitor (SC) simple converter ...
Kei Eguchi   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design of mine cascade converter with wide input voltage range

open access: yesGong-kuang zidonghua, 2022
The converter used in the power supply has problems of low voltage gain, high voltage stress of power tube, non-electrical isolation and complex control.
LIU Yangqing, ZHOU Yuan
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Induction machine at unity power factor with rotating power electronic converter

open access: yes, 2012
A new configuration for the self-excitation of the induction machine invented by Magnus Lindmark is presented. The power electronic converter using solid state switches is connected to the rotor while the stator is directly connected to the grid.
Chandur Sadarangani   +7 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Design of SiC-Si Hybrid Interleaved 3-Phase 5-Level E-Type Back-to-Back Converter

open access: yesIEEE Open Journal of Power Electronics, 2023
In modern applications, such as variable frequency electric drives, aircraft propulsion, electric vehicles, and uninterruptible power supply units, high power-dense, and efficient AC-AC power converters are the key to reducing power losses, thus limiting
Marco di Benedetto   +2 more
doaj   +1 more source

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