Results 41 to 50 of about 4,857,649 (284)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Analysis of an LLC–DAB integrated DC–DC converter topology with low loss and low cost

IET Power Electronics, 2023
This paper proposes an LLC‐DAB integrated high‐frequency isolated DC–DC converter topology structure to reduce the loss and cost of the DC power distribution system. Furthermore, the complexity and efficiency of the system also can be improved.
Shichong Zhang, Dezhi Chen, Baodong Bai, Zhonghuan Su   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

AC-DC PFC Converter Using Combination of Flyback Converter and Full-bridge DC-DC Converter

Emitter: International Journal of Engineering Technology, 2014
This paper presents a combination of power factor correction converter using Flyback converter and Full-bridge dc-dc converter in series connection. Flyback converter is operated in discontinuous conduction mode so that it can serve as a power factor ...
Moh. Zaenal Efendi, Abdul Rizal, Aldi Erzanuari, Suryono ., Novie Ayub Windarko   +4 more
doaj   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Electromagnetic Transient Simulation Algorithm for Nonlinear Elements Based on Rosenbrock Numerical Integration Method

IEEE Access
Traditional nonlinear elements of the electromagnetic transient simulation program (EMTP) use the numerical integration method, often employing the trapezoidal integration method as an implicit algorithm. However, when the number of nonlinear elements is
Jing Ye, Jihao Xie, Yong Wang, Liang Zhang, Binshan Li, Jinwei Lv, Ke Li, Shengpeng Jin, Yang Xu, Wei Ma   +9 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Maximum power point tracking‐based model predictive control with reduced sensor count for PV applications

IET Renewable Power Generation
This paper discusses the MPPT based on finite‐set model predictive control (FS‐MPC) in photovoltaic (PV) systems. Generally, the FS‐MPC implementation needs more sensors in comparison with the traditional methods due to the existence of the prediction ...
Mostafa Ahmed, Ibrahim Harbi, Christoph M. Hackl, Ralph Kennel, Jose Rodriguez, Mohamed Abdelrahem   +5 more
doaj   +1 more source

DC-DC Boost Converter with Constant Output Voltage for Grid Connected Photovoltaic Application System [PDF]

, 2010
The main purpose of this paper is to introduce an approach to design a DC-DC boost converter with constant output voltage for grid connected photovoltaic application system.
Chan, Pui Weng
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