Results 51 to 60 of about 4,857,649 (284)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Nomenclature Overview and Beat Frequency in the Family of AC/AC Modular Multilevel Cascade Converters (MMCC)

IEEE Access
The family of modular multilevel cascade converter (MMCC) has gained significant attention owing to its modular configuration, scalability, and superior harmonic performance.
Mohammed Azharuddin Shamshuddin, Ralph M. Kennel, Diego Verdugo   +2 more
doaj   +1 more source

Fault-tolerance Design and Validation of Power Converter [PDF]

Jisuanji gongcheng, 2017
In order to improve the reliability of the Switch Reluctance Generation(SRG)system,several common failures of power converter are analyzed.Combined with the superiority of the independence of asymmetrical bridge power converter,a kind of fault-tolerant ...
ZHOU Zheng,LIU Yongzhi,SONG Jinlong,MA Weimin,WANG Zhenliang
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Small-Signal Analysis of Permanent Magnet Synchronous Machines Under Scalar Control for Subsea Applications

IEEE Open Journal of Industry Applications
Recent solutions for oil and gas production have driven companies to operate in increasingly harsh environments, necessitating the development of more complex subsea variable speed drives (VSDs).
Esio Eloi dos Santos Filho, Marcelo Lobo Heldwein   +1 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

App-Based Tool for Automatic Controller Parameters Assessment for Power Converters in Particle Accelerator Facilities

IEEE Open Journal of Industry Applications
Regulation coefficients assessment in a particle accelerator power conversion system depends on the topology, the magnet and the desired transient response. The series/parallel combination of a generic power converter (a brick) to develop a larger one (e.
Sebastian O. Maestri, Gilles Legodec, Olivier Michels   +2 more
doaj   +1 more source

An Overview of Applications of the Modular Multilevel Matrix Converter

Energies, 2020
The modular multilevel matrix converter is a relatively new power converter topology suitable for high-power alternating current (AC)-to-AC applications.
Matias Diaz, Roberto Cárdenas Dobson, Efrain Ibaceta, Andrés Mora, Matias Urrutia, Mauricio Espinoza, Felix Rojas, Patrick Wheeler   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Design and Model-Based Evaluation of Active Clamping for Solid-State Circuit Breakers in Vehicular Power Supply Systems

IEEE Open Journal of Power Electronics
Solid-state circuit breakers, in vehicles also known as electronic fuses, isolate faults faster than conventional blade fuses and offer advanced protection mechanisms.
Bastian Eisenmann, Martin Baumann, Christoph Mayer, Marcelo Lobo Heldwein   +3 more
doaj   +1 more source