Results 51 to 60 of about 343,485 (300)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

AC-DC PFC Converter Using Combination of Flyback Converter and Full-bridge DC-DC Converter

Emitter: International Journal of Engineering Technology, 2014
This paper presents a combination of power factor correction converter using Flyback converter and Full-bridge dc-dc converter in series connection. Flyback converter is operated in discontinuous conduction mode so that it can serve as a power factor ...
Moh. Zaenal Efendi, Abdul Rizal, Aldi Erzanuari, Suryono ., Novie Ayub Windarko   +4 more
doaj   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pseudo-saturating power converter [PDF]

, 1972
Relative performance of three basic configurations of electronic conversion units (saturating, pseudo-saturating, nonsaturating) requiring low power levels is compared.
Agnew, C. V., Radys, R. G.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Electromagnetic Transient Simulation Algorithm for Nonlinear Elements Based on Rosenbrock Numerical Integration Method

IEEE Access
Traditional nonlinear elements of the electromagnetic transient simulation program (EMTP) use the numerical integration method, often employing the trapezoidal integration method as an implicit algorithm. However, when the number of nonlinear elements is
Jing Ye, Jihao Xie, Yong Wang, Liang Zhang, Binshan Li, Jinwei Lv, Ke Li, Shengpeng Jin, Yang Xu, Wei Ma   +9 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Maximum power point tracking‐based model predictive control with reduced sensor count for PV applications

IET Renewable Power Generation
This paper discusses the MPPT based on finite‐set model predictive control (FS‐MPC) in photovoltaic (PV) systems. Generally, the FS‐MPC implementation needs more sensors in comparison with the traditional methods due to the existence of the prediction ...
Mostafa Ahmed, Ibrahim Harbi, Christoph M. Hackl, Ralph Kennel, Jose Rodriguez, Mohamed Abdelrahem   +5 more
doaj   +1 more source

Fault-tolerance Design and Validation of Power Converter [PDF]

Jisuanji gongcheng, 2017
In order to improve the reliability of the Switch Reluctance Generation(SRG)system,several common failures of power converter are analyzed.Combined with the superiority of the independence of asymmetrical bridge power converter,a kind of fault-tolerant ...
ZHOU Zheng,LIU Yongzhi,SONG Jinlong,MA Weimin,WANG Zhenliang
doaj   +1 more source